Pilot Study of Pencil Beam Scanning Proton Beam Radiation Therapy in Patients With Renal Tumors
Who is this study for? Patients with renal tumors
What treatments are being studied? Proton beam radiation using pencil beam scanning
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 30
Healthy Volunteers: f
View:
• Less than 30 years of age
• Diagnosis
• a. Any patient with Wilms tumor or clear cell sarcoma of the kidney who would require radiation therapy as standard of care including
⁃ Any patient with favorable histology (FH), stage III disease
⁃ Any patient with focal or diffuse anaplasia
⁃ Any patient with CCSK
• The patient is a candidate for external beam radiotherapy based on standard of care for treatment of Wilms tumor or CCSK
Locations
United States
Pennsylvania
Children's Hospital of Philadelphia
RECRUITING
Philadelphia
Contact Information
Primary
Christine Hill-Kayser, MD
hill@uphs.upenn.edu
215-590-2810
Backup
Ratnakar Patti
PATTIR@chop.edu
Time Frame
Start Date: 2017-12-26
Estimated Completion Date: 2027-10-30
Participants
Target number of participants: 28
Treatments
Other: Renal tumors
Any patient with Wilms tumor or clear cell sarcoma of the kidney who would require radiation therapy as standard of care. Patients may receive an investigation drug for Wilms or CCSK given concurrently or within the first four weeks of the first fraction of proton therapy administration.
Related Therapeutic Areas
Sponsors
Leads: Children's Hospital of Philadelphia