A J. Challiss

Lancaster Road
Leicester, ENG LE17RH, United Kingdom

Last Updated: 09/26/2026

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Found 19 publications

GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation.

GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation.

Journal: Biochemical pharmacology

Published: July 10, 2023

Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle.

Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle.

Journal: Cellular signalling

Published: April 19, 2018

Small-Molecule G Protein-Coupled Receptor Kinase Inhibitors Attenuate G Protein-Coupled Receptor Kinase 2-Mediated Desensitization of Vasoconstrictor-Induced Arterial Contractions.

Small-Molecule G Protein-Coupled Receptor Kinase Inhibitors Attenuate G Protein-Coupled Receptor Kinase 2-Mediated Desensitization of Vasoconstrictor-Induced Arterial Contractions.

Journal: Molecular pharmacology

Published: March 23, 2018

Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor.

Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor.

Journal: Molecular pharmacology

Published: November 08, 2017

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.

Journal: PLoS biology

Published: July 18, 2017

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4.

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4.

Journal: The Journal of allergy and clinical immunology

Published: February 29, 2016

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory.

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory.

Journal: The Journal of biological chemistry

Published: July 29, 2015

Biosynthetic infochemical communication.

Biosynthetic infochemical communication.

Journal: Bioinspiration & biomimetics

Published: July 10, 2015

British Pharmacological Society, 5th Focused Meeting on Cell Signalling: Matters arising ….

British Pharmacological Society, 5th Focused Meeting on Cell Signalling: Matters arising ….

Journal: British journal of pharmacology

Published: June 23, 2015

Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose.

Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose.

Journal: British journal of pharmacology

Published: June 18, 2015

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.

Journal: American journal of physiology. Cell physiology

Published: March 18, 2015

Steady-state modulation of voltage-gated K+ channels in rat arterial smooth muscle by cyclic AMP-dependent protein kinase and protein phosphatase 2B.

Steady-state modulation of voltage-gated K+ channels in rat arterial smooth muscle by cyclic AMP-dependent protein kinase and protein phosphatase 2B.

Journal: PloS one

Published: August 04, 2014

Showing 1-12 of 19

Last Updated: 09/26/2026