Aashish Soni

Essen, NW 45147, Germany

Last Updated: 09/26/2026

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Found 32 publications

Evidence for Quasi-High-LET Biological Effects in Clinical Proton Beams That Suppress c-NHEJ and Enhance HR and Alt-EJ.

Evidence for Quasi-High-LET Biological Effects in Clinical Proton Beams That Suppress c-NHEJ and Enhance HR and Alt-EJ.

Journal: Cells

Published: December 03, 2025

Condensins regulate resection-dependent DNA double-strand break repair pathways in replicated chromatin.

Condensins regulate resection-dependent DNA double-strand break repair pathways in replicated chromatin.

Journal: Nucleic acids research

Published: August 06, 2025

Homologous Recombination and Alternative End-Joining Repair Pathways are Important Determinants of Radiosensitivity to Proton Radiation Therapy.

Homologous Recombination and Alternative End-Joining Repair Pathways are Important Determinants of Radiosensitivity to Proton Radiation Therapy.

Journal: International journal of radiation oncology, biology, physics

Published: June 26, 2025

Reversing regulatory safeguards: Targeting the ATR pathway to overcome PARP inhibitor resistance.

Reversing regulatory safeguards: Targeting the ATR pathway to overcome PARP inhibitor resistance.

Journal: Molecular therapy. Oncology

Published: February 19, 2025

NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast Cells.

NGS Detects Extensive Genomic Alterations in Survivors of Irradiated Normal Human Fibroblast Cells.

Journal: Radiation research

Published: March 28, 2024

Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Polθ inhibition.

Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Polθ inhibition.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Published: December 19, 2023

The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.

The p38/MK2 Pathway Functions as Chk1-Backup Downstream of ATM/ATR in G2-Checkpoint Activation in Cells Exposed to Ionizing Radiation.

Journal: Cells

Published: March 21, 2023

Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.

Low CDK Activity and Enhanced Degradation by APC/CCDH1 Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.

Journal: Cells

Published: March 17, 2023

BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.

BMN673 Is a PARP Inhibitor with Unique Radiosensitizing Properties: Mechanisms and Potential in Radiation Therapy.

Journal: Cancers

Published: October 07, 2022

PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.

PTEN Loss Enhances Error-Prone DSB Processing and Tumor Cell Radiosensitivity by Suppressing RAD51 Expression and Homologous Recombination.

Journal: International journal of molecular sciences

Published: September 19, 2022

Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.

Increased Resection at DSBs in G2-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.

Journal: Cells

Published: June 02, 2022

ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.

ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions.

Journal: International journal of molecular sciences

Published: May 30, 2022

Showing 1-12 of 32

Last Updated: 09/26/2026