Abdallah Derbalah

Level 2-Acero, 1 Concourse Way
Sheffield, ENG S12BJ, United Kingdom

Last Updated: 09/26/2026

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Found 15 publications

Correction: Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Correction: Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Journal: Journal of pharmacokinetics and pharmacodynamics

Published: July 30, 2025

PBPK Modelling of Antisense Oligonucleotide Therapeutics: Application for Predicting Plasma and Tissue Pharmacokinetics of Bepirovirsen.

PBPK Modelling of Antisense Oligonucleotide Therapeutics: Application for Predicting Plasma and Tissue Pharmacokinetics of Bepirovirsen.

Journal: The AAPS journal

Published: July 08, 2025

Modeling and Simulation Identifies Endocytosis Uptake Rate and Fraction Unbound as Important Predictors of Oligonucleotide Pharmacokinetics.

Modeling and Simulation Identifies Endocytosis Uptake Rate and Fraction Unbound as Important Predictors of Oligonucleotide Pharmacokinetics.

Journal: CPT: pharmacometrics & systems pharmacology

Published: June 23, 2025

Mechanistic Insights into Cytokine Antagonist-Drug Interactions: A Physiologically Based Pharmacokinetic Modelling Approach with Tocilizumab as a Case Study.

Mechanistic Insights into Cytokine Antagonist-Drug Interactions: A Physiologically Based Pharmacokinetic Modelling Approach with Tocilizumab as a Case Study.

Journal: Pharmaceutics

Published: May 31, 2025

The physiological limits of bispecific monoclonal antibody tissue targeting specificity.

The physiological limits of bispecific monoclonal antibody tissue targeting specificity.

Journal: mAbs

Published: April 14, 2025

Accelerating Biologics PBPK Modelling with Automated Model Building: A Tutorial.

Accelerating Biologics PBPK Modelling with Automated Model Building: A Tutorial.

Journal: Pharmaceutics

Published: March 29, 2025

Physiologically Based Pharmacokinetic Modeling of Biologic Case Studies in Monkeys and Humans Reveals the Necessity of an Additional Clearance Term.

Physiologically Based Pharmacokinetic Modeling of Biologic Case Studies in Monkeys and Humans Reveals the Necessity of an Additional Clearance Term.

Journal: Pharmaceutics

Published: March 09, 2025

Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Cross-species translational modelling of targeted therapeutic oligonucleotides using physiologically based pharmacokinetics.

Journal: Journal of pharmacokinetics and pharmacodynamics

Published: January 29, 2025

The role of automation in enhancing reproducibility and interoperability of PBPK models.

The role of automation in enhancing reproducibility and interoperability of PBPK models.

Journal: Briefings in bioinformatics

Published: January 06, 2025

A Physiologically Based Pharmacokinetic Model Relates the Subcutaneous Bioavailability of Monoclonal Antibodies to the Saturation of FcRn-Mediated Recycling in Injection-Site-Draining Lymph Nodes.

A Physiologically Based Pharmacokinetic Model Relates the Subcutaneous Bioavailability of Monoclonal Antibodies to the Saturation of FcRn-Mediated Recycling in Injection-Site-Draining Lymph Nodes.

Journal: Antibodies (Basel, Switzerland)

Published: July 09, 2024

Optimal dosing of enoxaparin in overweight and obese children.

Optimal dosing of enoxaparin in overweight and obese children.

Journal: British journal of clinical pharmacology

Published: January 20, 2022

Reduction of quantitative systems pharmacology models using artificial neural networks.

Reduction of quantitative systems pharmacology models using artificial neural networks.

Journal: Journal of pharmacokinetics and pharmacodynamics

Published: October 27, 2020

Showing 1-12 of 15

Last Updated: 09/26/2026