Abdelsamed I. Elshamy

El Tahrir Street
Dokki, GZ 12622, Egypt

Last Updated: 09/26/2026

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Found 112 publications

Alogliptin mitigates doxorubicin-induced cardiotoxicity in rats: Implications of SIRT3/NRF2 pathway and miRNA-133a.

Alogliptin mitigates doxorubicin-induced cardiotoxicity in rats: Implications of SIRT3/NRF2 pathway and miRNA-133a.

Journal: Tissue & cell

Published: June 10, 2026

Discovery of novel anti-Toxoplasma gondii agent derived from thiazolidinone-isatin hybrids: synthesis, biological assessment, and computational modeling.

Discovery of novel anti-Toxoplasma gondii agent derived from thiazolidinone-isatin hybrids: synthesis, biological assessment, and computational modeling.

Journal: RSC advances

Published: May 28, 2026

Polyphenol-rich Dactyloctenium aegyptium extract protects against aspirin or ethanol-induced gastric ulcers via antioxidant, anti-inflammatory, and anti-apoptotic pathways.

Polyphenol-rich Dactyloctenium aegyptium extract protects against aspirin or ethanol-induced gastric ulcers via antioxidant, anti-inflammatory, and anti-apoptotic pathways.

Journal: Tissue & cell

Published: April 06, 2026

Guazuma ulmifolia butanol extract protects against cadmium-induced hepatotoxicity via HO-1/Sirt-1 activation, miRNA-lncRNA modulation, and metabolic reprogramming.

Guazuma ulmifolia butanol extract protects against cadmium-induced hepatotoxicity via HO-1/Sirt-1 activation, miRNA-lncRNA modulation, and metabolic reprogramming.

Journal: PloS one

Published: February 11, 2026

UPLC-ESI-qTOF-MS metabolomic characterization and in vivo neuroprotective activity of Diplotaxis harra ethanolic extract through antioxidant, anti-cholinesterase, and anti-amyloid mechanisms.

UPLC-ESI-qTOF-MS metabolomic characterization and in vivo neuroprotective activity of Diplotaxis harra ethanolic extract through antioxidant, anti-cholinesterase, and anti-amyloid mechanisms.

Journal: Fitoterapia

Published: January 27, 2026

Metabolite-rich Saccharomyces cerevisiae cell wall extract counter diabetic tissue damage via AMPK activation and microbiome modulation in rats.

Metabolite-rich Saccharomyces cerevisiae cell wall extract counter diabetic tissue damage via AMPK activation and microbiome modulation in rats.

Journal: Tissue & cell

Published: December 07, 2025

Investigation of Potent Anti-Mycobacterium tuberculosis Agents Derived from Pyridine Derivatives Targeting the Enoyl Acyl Carrier Protein Reductase (InhA): Design, Synthesis, and Computational Analysis.

Investigation of Potent Anti-Mycobacterium tuberculosis Agents Derived from Pyridine Derivatives Targeting the Enoyl Acyl Carrier Protein Reductase (InhA): Design, Synthesis, and Computational Analysis.

Journal: Drug design, development and therapy

Published: September 30, 2025

Assessment of the therapeutic efficacy of rutin-loaded PLGA nanocapsule-based gel against imiquimod-induced psoriasis model using box-behnken design for optimization.

Assessment of the therapeutic efficacy of rutin-loaded PLGA nanocapsule-based gel against imiquimod-induced psoriasis model using box-behnken design for optimization.

Journal: International journal of pharmaceutics

Published: September 16, 2025

Bioactive-rich Mangifera indica leaf extracts alleviate inflammation, pain, and fever via suppression of pro-inflammatory cytokines and activation of Nrf2 pathways.

Bioactive-rich Mangifera indica leaf extracts alleviate inflammation, pain, and fever via suppression of pro-inflammatory cytokines and activation of Nrf2 pathways.

Journal: Tissue & cell

Published: September 11, 2025

Synergistic wound healing mechanisms of Heliotropium curassavicum extracts via redox modulation, inflammation suppression, and tissue remodeling: linking phytochemical diversity to antioxidant and anti-inflammatory effects.

Synergistic wound healing mechanisms of Heliotropium curassavicum extracts via redox modulation, inflammation suppression, and tissue remodeling: linking phytochemical diversity to antioxidant and anti-inflammatory effects.

Journal: Inflammopharmacology

Published: August 14, 2025

An exploration of potent antileishmanial agents derived from quinoline-thiazole and thiadiazole hybrids, targeting DHFR-TS and PTR1: design, synthesis, and computational analyses.

An exploration of potent antileishmanial agents derived from quinoline-thiazole and thiadiazole hybrids, targeting DHFR-TS and PTR1: design, synthesis, and computational analyses.

Journal: RSC medicinal chemistry

Published: August 13, 2025

Multitarget Antioxidant and Anticancer Potential of Euphorbia greenwayi Essential Oil: Phytochemical Profiling and Molecular Insights.

Multitarget Antioxidant and Anticancer Potential of Euphorbia greenwayi Essential Oil: Phytochemical Profiling and Molecular Insights.

Journal: Chemistry & biodiversity

Published: June 04, 2025

Showing 1-12 of 112

Last Updated: 09/26/2026