Abid Oueslati

Laval, QC G1V0A6, Canada

Last Updated: 09/26/2026

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Found 37 publications

Modeling Parkinson's pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity.

Modeling Parkinson's pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity.

Journal: Science advances

Published: July 10, 2026

WDR44 drives de novo α-synuclein aggregation at the lysosomal membrane and promotes neuronal dysfunction in Parkinson's Disease.

WDR44 drives de novo α-synuclein aggregation at the lysosomal membrane and promotes neuronal dysfunction in Parkinson's Disease.

Journal: bioRxiv : the preprint server for biology

Published: April 17, 2026

Protocol for dissecting the aggregation-prone protein interactome with optogenetic-induced aggregation and biotin labeling proximity assay.

Protocol for dissecting the aggregation-prone protein interactome with optogenetic-induced aggregation and biotin labeling proximity assay.

Journal: STAR protocols

Published: October 08, 2025

The emerging role of polo-like kinase 2 in Alzheimer's disease.

The emerging role of polo-like kinase 2 in Alzheimer's disease.

Journal: Experimental neurology

Published: August 31, 2025

Interplay between lipid droplets and alpha-synuclein: implication in Parkinson's disease pathogenesis.

Interplay between lipid droplets and alpha-synuclein: implication in Parkinson's disease pathogenesis.

Journal: Frontiers in molecular neuroscience

Published: August 06, 2025

Optogenetic-induced α-synuclein accumulation reveals early synaptic dysfunction in experimental models of Parkinson's disease.

Optogenetic-induced α-synuclein accumulation reveals early synaptic dysfunction in experimental models of Parkinson's disease.

Journal: NPJ Parkinson's disease

Published: July 23, 2025

The impact of tau deletion on Huntington's disease: An in vivo perspective.

The impact of tau deletion on Huntington's disease: An in vivo perspective.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: May 21, 2025

Combining light-induced aggregation and biotin proximity labeling implicates endolysosomal proteins in early α-synuclein oligomerization.

Combining light-induced aggregation and biotin proximity labeling implicates endolysosomal proteins in early α-synuclein oligomerization.

Journal: iScience

Published: October 16, 2024

Pharmacological inhibition of PLK2 kinase activity mitigates cognitive decline but aggravates APP pathology in a sex-dependent manner in APP/PS1 mouse model of Alzheimer's disease.

Pharmacological inhibition of PLK2 kinase activity mitigates cognitive decline but aggravates APP pathology in a sex-dependent manner in APP/PS1 mouse model of Alzheimer's disease.

Journal: Heliyon

Published: August 22, 2024

Behavioral analysis of motor and non-motor impairment in rodent models of Parkinson's disease.

Behavioral analysis of motor and non-motor impairment in rodent models of Parkinson's disease.

Journal: Frontiers in aging neuroscience

Published: July 15, 2024

Corrigendum to "Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease" [Neurobiology of Disease, 2024 Jan:190:106376].

Corrigendum to "Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease" [Neurobiology of Disease, 2024 Jan:190:106376].

Journal: Neurobiology of disease

Published: February 24, 2024

Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease.

Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease.

Journal: Neurobiology of disease

Published: October 02, 2023

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Last Updated: 09/26/2026