Achim J. Sauer

Biberach An Der Riss, BW, Germany

Last Updated: 09/26/2026

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Found 18 publications

Breaking Barriers Between Species: Integrated Multi-Species PK Models Improve Human PK Predictions.

Breaking Barriers Between Species: Integrated Multi-Species PK Models Improve Human PK Predictions.

Journal: CPT: pharmacometrics & systems pharmacology

Published: November 28, 2025

Beyond CL and VSS: A comprehensive approach to human pharmacokinetic predictions.

Beyond CL and VSS: A comprehensive approach to human pharmacokinetic predictions.

Journal: Drug discovery today

Published: August 03, 2024

Towards holistic Compound Quality Scores: Extending ligand efficiency indices with compound pharmacokinetic characteristics.

Towards holistic Compound Quality Scores: Extending ligand efficiency indices with compound pharmacokinetic characteristics.

Journal: Drug discovery today

Published: May 09, 2023

LC/MS Assessment of Glycoform Clearance of A Biotherapeutic MAb in Rabbit Ocular Tissues.

LC/MS Assessment of Glycoform Clearance of A Biotherapeutic MAb in Rabbit Ocular Tissues.

Journal: Journal of pharmaceutical sciences

Published: February 08, 2023

Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations.

Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations.

Journal: International journal of pharmaceutics

Published: October 11, 2021

Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells.

Nanchangmycin regulates FYN, PTK2, and MAPK1/3 to control the fibrotic activity of human hepatic stellate cells.

Journal: eLife

Published: October 07, 2021

A Bidirectional Permeability Assay for beyond Rule of 5 Compounds.

A Bidirectional Permeability Assay for beyond Rule of 5 Compounds.

Journal: Pharmaceutics

Published: June 28, 2021

Mechanistic Model for the Prediction of Small-Molecule Vitreal Clearance Combining Diffusion-Limited and Permeability-Limited Clearance.

Mechanistic Model for the Prediction of Small-Molecule Vitreal Clearance Combining Diffusion-Limited and Permeability-Limited Clearance.

Journal: Molecular pharmaceutics

Published: June 21, 2021

Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues.

Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues.

Journal: Molecular pharmaceutics

Published: February 17, 2021

Quantification of Drugs in Distinctly Separated Ocular Substructures of Albino and Pigmented Rats.

Quantification of Drugs in Distinctly Separated Ocular Substructures of Albino and Pigmented Rats.

Journal: Pharmaceutics

Published: November 13, 2020

Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood-Brain Barrier and Its Implementation into Compound Optimization in Drug Discovery.

Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood-Brain Barrier and Its Implementation into Compound Optimization in Drug Discovery.

Journal: Pharmaceutics

Published: October 02, 2019

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 28, 2019

Showing 1-12 of 18

Last Updated: 09/26/2026