Adam J. Carlton

Sheffield, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 14 publications

Aging Alters Hair Cell Physiological Properties in Mice With Late-Onset Age-Related Hearing Loss.

Aging Alters Hair Cell Physiological Properties in Mice With Late-Onset Age-Related Hearing Loss.

Journal: Aging cell

Published: November 21, 2025

Myosin 7a is required for maintaining the transducing stereocilia and for force transmission to the MET channel during cochlear hair cell development.

Myosin 7a is required for maintaining the transducing stereocilia and for force transmission to the MET channel during cochlear hair cell development.

Journal: The Journal of physiology

Published: June 27, 2025

Adeno-associated virus-based rescue of Myo7a expression restores hair-cell function and improves hearing thresholds in a USH1B mouse strain.

Adeno-associated virus-based rescue of Myo7a expression restores hair-cell function and improves hearing thresholds in a USH1B mouse strain.

Journal: The Journal of physiology

Published: June 18, 2025

MYO7A is required for the functional integrity of the mechanoelectrical transduction complex in hair cells of the adult cochlea.

MYO7A is required for the functional integrity of the mechanoelectrical transduction complex in hair cells of the adult cochlea.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 02, 2025

In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells.

In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells.

Journal: JCI insight

Published: April 16, 2024

The upregulation of K+ and HCN channels in developing spiral ganglion neurons is mediated by cochlear inner hair cells.

The upregulation of K+ and HCN channels in developing spiral ganglion neurons is mediated by cochlear inner hair cells.

Journal: The Journal of physiology

Published: December 14, 2023

BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing.

BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing.

Journal: Cell reports

Published: September 14, 2023

A critical period of prehearing spontaneous Ca2+ spiking is required for hair-bundle maintenance in inner hair cells.

A critical period of prehearing spontaneous Ca2+ spiking is required for hair-bundle maintenance in inner hair cells.

Journal: The EMBO journal

Published: July 16, 2022

AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness.

AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness.

Journal: Molecular therapy. Methods & clinical development

Published: April 30, 2022

Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.

Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.

Journal: PLoS genetics

Published: November 09, 2021

MET currents and otoacoustic emissions from mice with a detached tectorial membrane indicate the extracellular matrix regulates Ca2+ near stereocilia.

MET currents and otoacoustic emissions from mice with a detached tectorial membrane indicate the extracellular matrix regulates Ca2+ near stereocilia.

Journal: The Journal of physiology

Published: October 02, 2020

Loss of Baiap2l2 destabilizes the transducing stereocilia of cochlear hair cells and leads to deafness.

Loss of Baiap2l2 destabilizes the transducing stereocilia of cochlear hair cells and leads to deafness.

Journal: The Journal of physiology

Published: August 16, 2020

Showing 1-12 of 14

Last Updated: 09/26/2026