Adam Mieczkowski

Warsaw, MZ 02106, Poland

Last Updated: 09/26/2026

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Found 21 publications

The discovery of potent and selective N6-modified adenosine derivatives as effective chemotherapeutic agents to overcome p53-dependent drug resistance in cancer and HPIV-3/AdV5 respiratory tract infections.

The discovery of potent and selective N6-modified adenosine derivatives as effective chemotherapeutic agents to overcome p53-dependent drug resistance in cancer and HPIV-3/AdV5 respiratory tract infections.

Journal: Bioorganic chemistry

Published: February 06, 2026

Modulating backbone flexibility in hydroxamate siderophores for improved iron chelation and peptide nucleic acid delivery into bacteria.

Modulating backbone flexibility in hydroxamate siderophores for improved iron chelation and peptide nucleic acid delivery into bacteria.

Journal: The Biochemical journal

Published: September 30, 2025

Triazolo[4,5-d]pyrimidin-5-amines based ERK3 inhibitors fail to demonstrate selective effects on adipocyte function.

Triazolo[4,5-d]pyrimidin-5-amines based ERK3 inhibitors fail to demonstrate selective effects on adipocyte function.

Journal: Archives of biochemistry and biophysics

Published: July 25, 2023

Synthesis and applications of cyclonucleosides: an update (2010-2023).

Synthesis and applications of cyclonucleosides: an update (2010-2023).

Journal: Molecular diversity

Published: July 07, 2023

Designing multi-target-directed flavonoids: a strategic approach to Alzheimer's disease.

Designing multi-target-directed flavonoids: a strategic approach to Alzheimer's disease.

Journal: Chemical science

Published: February 10, 2023

Dimeric Benzodiazepines as Peptide Mimetics to Overcome p53-Dependent Drug Resistance of Tumors.

Dimeric Benzodiazepines as Peptide Mimetics to Overcome p53-Dependent Drug Resistance of Tumors.

Journal: Biomolecules

Published: December 15, 2022

Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold.

Cyclic Dipeptides: The Biological and Structural Landscape with Special Focus on the Anti-Cancer Proline-Based Scaffold.

Journal: Biomolecules

Published: September 18, 2021

Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues.

Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: July 28, 2021

Synthesis and evaluation of adenosine derivatives as A1, A2A, A2B and A3 adenosine receptor ligands containing boron clusters as phenyl isosteres and selective A3 agonists.

Synthesis and evaluation of adenosine derivatives as A1, A2A, A2B and A3 adenosine receptor ligands containing boron clusters as phenyl isosteres and selective A3 agonists.

Journal: European journal of medicinal chemistry

Published: January 27, 2021

Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile.

Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile.

Journal: Molecules (Basel, Switzerland)

Published: January 08, 2021

Internalization of the Aspergillus nidulans AstA Transporter into Mitochondria Depends on Growth Conditions, and Affects ATP Levels and Sulfite Oxidase Activity.

Internalization of the Aspergillus nidulans AstA Transporter into Mitochondria Depends on Growth Conditions, and Affects ATP Levels and Sulfite Oxidase Activity.

Journal: International journal of molecular sciences

Published: September 22, 2020

Design and in Vitro Characterization of Tricyclic Benzodiazepine Derivatives as Potent and Selective Antileukemic Agents.

Design and in Vitro Characterization of Tricyclic Benzodiazepine Derivatives as Potent and Selective Antileukemic Agents.

Journal: Chemistry & biodiversity

Published: September 05, 2020

Showing 1-12 of 21

Last Updated: 09/26/2026