Adel S. Girgis

Giza, GZ 12622, Egypt

Last Updated: 09/26/2026

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Found 76 publications

Multifunctional Curcumin-Inspired 3,5-Diarylidene-4-Piperidones: Design, Synthesis, Biological Evaluation and Computational Mechanistic Studies.

Multifunctional Curcumin-Inspired 3,5-Diarylidene-4-Piperidones: Design, Synthesis, Biological Evaluation and Computational Mechanistic Studies.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: May 08, 2026

Antineoplastic multi-targeted spiro[indoline-3,2'-pyrrolidines] incorporating urea function: Rational design, synthesis and bio-properties studies.

Antineoplastic multi-targeted spiro[indoline-3,2'-pyrrolidines] incorporating urea function: Rational design, synthesis and bio-properties studies.

Journal: Bioorganic chemistry
Published: February 01, 2026

Hybrid molecules of ibuprofen and piperidone: a rational approach toward anti-cancer drug development.

Hybrid molecules of ibuprofen and piperidone: a rational approach toward anti-cancer drug development.

Journal: Bioorganic & medicinal chemistry
Published: July 23, 2025

Antiproliferation, 3D-multicellular spheroid and VEGFR-2 inhibitory properties of spiroindolin-2-ones with phosphonate function.

Antiproliferation, 3D-multicellular spheroid and VEGFR-2 inhibitory properties of spiroindolin-2-ones with phosphonate function.

Journal: Scientific reports
Published: July 07, 2025

Hybrid Conjugates of Ibuprofen and 3,5-Diarylidene-4-Piperidone: A New Avenue in Anti-Inflammatory Drug Discovery.

Hybrid Conjugates of Ibuprofen and 3,5-Diarylidene-4-Piperidone: A New Avenue in Anti-Inflammatory Drug Discovery.

Journal: ChemMedChem
Published: May 01, 2025

Antineoplastic 4-piperidone-1-phosphonothioates with potential multi-targeted inhibitory properties.

Antineoplastic 4-piperidone-1-phosphonothioates with potential multi-targeted inhibitory properties.

Journal: Scientific reports
Published: April 27, 2025

Novel isatin conjugates endowed with analgesic and anti-inflammatory properties: design, synthesis and biological evaluation.

Novel isatin conjugates endowed with analgesic and anti-inflammatory properties: design, synthesis and biological evaluation.

Journal: Future medicinal chemistry
Published: December 16, 2024

The Therapeutic Potential of Spirooxindoles in Cancer: A Focus on p53-MDM2 Modulation.

The Therapeutic Potential of Spirooxindoles in Cancer: A Focus on p53-MDM2 Modulation.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: December 13, 2024

Curcumin mimics of potential chemoprevention with NQO1 induction properties.

Curcumin mimics of potential chemoprevention with NQO1 induction properties.

Journal: Scientific reports
Published: October 07, 2024

Design and synthesis of antiproliferative 2-oxoindolin-3-ylidenes incorporating urea function with potential VEGFR-2 inhibitory properties.

Design and synthesis of antiproliferative 2-oxoindolin-3-ylidenes incorporating urea function with potential VEGFR-2 inhibitory properties.

Journal: Scientific reports
Published: July 31, 2024

Indole Compounds in Oncology: Therapeutic Potential and Mechanistic Insights.

Indole Compounds in Oncology: Therapeutic Potential and Mechanistic Insights.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: June 18, 2024

Antineoplastic indole-containing compounds with potential VEGFR inhibitory properties.

Antineoplastic indole-containing compounds with potential VEGFR inhibitory properties.

Journal: RSC advances
Published: December 31, 2023
Showing 1-12 of 76

Last Updated: 09/26/2026