Afaf A. Malah-El

33 Kasr El Aini Street
Cairo, C 11562, Egypt

Last Updated: 09/26/2026

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Found 18 publications

New quinazoline derivatives with anti-inflammatory activity and computationally predicted PDE7A binding: synthesis, molecular modeling, and in silico pharmacokinetic evaluation.

New quinazoline derivatives with anti-inflammatory activity and computationally predicted PDE7A binding: synthesis, molecular modeling, and in silico pharmacokinetic evaluation.

Journal: Frontiers in pharmacology

Published: April 19, 2026

Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors.

Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors.

Journal: Frontiers in pharmacology

Published: February 20, 2024

Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives.

Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives.

Journal: Scientific reports

Published: January 06, 2024

Schiff bases as linker in the development of quinoline-sulfonamide hybrids as selective cancer-associated carbonic anhydrase isoforms IX/XII inhibitors: A new regioisomerism tactic.

Schiff bases as linker in the development of quinoline-sulfonamide hybrids as selective cancer-associated carbonic anhydrase isoforms IX/XII inhibitors: A new regioisomerism tactic.

Journal: Bioorganic chemistry

Published: October 12, 2022

Assessment of commitment to healthy daily habits and diets, preventive measures, and beliefs about natural products utilization during COVID-19 pandemic in certain population in Egypt and Saudi Arabia.

Assessment of commitment to healthy daily habits and diets, preventive measures, and beliefs about natural products utilization during COVID-19 pandemic in certain population in Egypt and Saudi Arabia.

Journal: Pharmacy practice

Published: June 26, 2022

Selective COX-2 Inhibitors: Road from Success to Controversy and the Quest for Repurposing.

Selective COX-2 Inhibitors: Road from Success to Controversy and the Quest for Repurposing.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 01, 2022

In Vitro Anticancer Activity Screening of Novel Fused Thiophene Derivatives as VEGFR-2/AKT Dual Inhibitors and Apoptosis Inducers.

In Vitro Anticancer Activity Screening of Novel Fused Thiophene Derivatives as VEGFR-2/AKT Dual Inhibitors and Apoptosis Inducers.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: May 01, 2022

Anti-inflammatory activity of pyridazinones: A review.

Anti-inflammatory activity of pyridazinones: A review.

Journal: Archiv der Pharmazie

Published: February 08, 2022

Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives.

Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives.

Journal: Molecules (Basel, Switzerland)

Published: August 26, 2021

New promising levofloxacin derivatives: Design, synthesis, cytotoxic activity screening, Topo2β polymerase inhibition assay, cell cycle apoptosis profile analysis.

New promising levofloxacin derivatives: Design, synthesis, cytotoxic activity screening, Topo2β polymerase inhibition assay, cell cycle apoptosis profile analysis.

Journal: Bioorganic chemistry

Published: February 20, 2021

New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation.

New pyridazine derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents; design, synthesis and biological evaluation.

Journal: Bioorganic chemistry

Published: July 23, 2019

Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents.

Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents.

Journal: European journal of medicinal chemistry

Published: December 03, 2018

Showing 1-12 of 18

Last Updated: 09/26/2026