Afaf H. Sagheer-El

Mansfield Road, OX1 3TA
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 88 publications

Non-enzymatic conversion of RNA sequence information into DNA by squaramide ligation for accurate RNA quantification.

Non-enzymatic conversion of RNA sequence information into DNA by squaramide ligation for accurate RNA quantification.

Journal: Communications chemistry

Published: December 14, 2025

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.

Journal: Research square

Published: December 03, 2025

Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability, Translation, and CRISPR-Cas9 Cleavage.

Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability, Translation, and CRISPR-Cas9 Cleavage.

Journal: ACS chemical biology

Published: November 06, 2025

New Approach to Assembling Nucleic Acid Dendrons on a Solid Phase.

New Approach to Assembling Nucleic Acid Dendrons on a Solid Phase.

Journal: Organic letters

Published: August 20, 2025

Enhancing cap-independent translation of linear mRNA.

Enhancing cap-independent translation of linear mRNA.

Journal: Nature communications

Published: August 05, 2025

Hierarchical Coordination of Polymerase Theta and RAD51 Resolves Clustered Replication Fork Collapse.

Hierarchical Coordination of Polymerase Theta and RAD51 Resolves Clustered Replication Fork Collapse.

Journal: bioRxiv : the preprint server for biology

Published: July 09, 2025

Synthesis, Biological Activity, and Molecular Dynamics Simulations of LNA-Charge Neutral Linkages for Enhanced Splice-Switching Antisense Oligonucleotides.

Synthesis, Biological Activity, and Molecular Dynamics Simulations of LNA-Charge Neutral Linkages for Enhanced Splice-Switching Antisense Oligonucleotides.

Journal: Angewandte Chemie (International ed. in English)

Published: May 24, 2025

Measurements of molecular size and shape on a chip.

Measurements of molecular size and shape on a chip.

Journal: Science (New York, N.Y.)

Published: May 08, 2025

Molecular insights into the stimulation of SNM1A nuclease activity by CSB during interstrand crosslink processing.

Molecular insights into the stimulation of SNM1A nuclease activity by CSB during interstrand crosslink processing.

Journal: bioRxiv : the preprint server for biology

Published: September 16, 2024

Modular and automated synthesis of oligonucleotide-small molecule conjugates for cathepsin B mediated traceless release of payloads.

Modular and automated synthesis of oligonucleotide-small molecule conjugates for cathepsin B mediated traceless release of payloads.

Journal: RSC chemical biology

Published: May 23, 2024

Synthesis and Properties of Oligonucleotides Containing LNA-Sulfamate and Sulfamide Backbone Linkages.

Synthesis and Properties of Oligonucleotides Containing LNA-Sulfamate and Sulfamide Backbone Linkages.

Journal: Organic letters

Published: May 08, 2024

Thiazole orange-carboplatin triplex-forming oligonucleotide (TFO) combination probes enhance targeted DNA crosslinking.

Thiazole orange-carboplatin triplex-forming oligonucleotide (TFO) combination probes enhance targeted DNA crosslinking.

Journal: RSC medicinal chemistry

Published: October 03, 2023

Showing 1-12 of 88

Last Updated: 09/26/2026