Agostino Marrazzo

Catania, Italy

Last Updated: 09/26/2026

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Found 96 publications

Mechano-Biocatalytic Stereoselective Reduction of Ketones With Baker's Yeast Under Solvent-Minimized Conditions.

Mechano-Biocatalytic Stereoselective Reduction of Ketones With Baker's Yeast Under Solvent-Minimized Conditions.

Journal: ChemSusChem

Published: February 26, 2026

Beyond conventional 5-Fluorouracil: Recent medicinal chemistry strategies to enhance its anticancer efficacy.

Beyond conventional 5-Fluorouracil: Recent medicinal chemistry strategies to enhance its anticancer efficacy.

Journal: European journal of medicinal chemistry

Published: February 16, 2026

Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ1R Agonists/HDAC Inhibitor Dual-Acting Compounds.

Modulation of Tau Protein Neurotoxic Hallmarks by Novel σ1R Agonists/HDAC Inhibitor Dual-Acting Compounds.

Journal: ChemMedChem

Published: October 16, 2025

Targeting histone deacetylase 1: Inhibition and activation as promising therapeutic strategies for diverse disorders.

Targeting histone deacetylase 1: Inhibition and activation as promising therapeutic strategies for diverse disorders.

Journal: European journal of medicinal chemistry

Published: May 31, 2025

HDAC/σ1R Dual-Ligand as a Targeted Melanoma Therapeutic.

HDAC/σ1R Dual-Ligand as a Targeted Melanoma Therapeutic.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: December 24, 2024

Enhancing HDAC Inhibitor Screening: Addressing Zinc Parameterization and Ligand Protonation in Docking Studies.

Enhancing HDAC Inhibitor Screening: Addressing Zinc Parameterization and Ligand Protonation in Docking Studies.

Journal: International journal of molecular sciences

Published: December 19, 2024

Design and Synthesis of Tetrahydropyrrolo[3,4-c]Pyrazole Sigma-1 Receptor Ligands.

Design and Synthesis of Tetrahydropyrrolo[3,4-c]Pyrazole Sigma-1 Receptor Ligands.

Journal: ChemMedChem

Published: December 18, 2024

Design, Synthesis, and Evaluation of Novel (-)-cis-N-Normetazocine Derivatives: In Vitro and Molecular Modeling Insights.

Design, Synthesis, and Evaluation of Novel (-)-cis-N-Normetazocine Derivatives: In Vitro and Molecular Modeling Insights.

Journal: Chemical biology & drug design

Published: September 16, 2024

Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds.

Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds.

Journal: European journal of medicinal chemistry

Published: September 13, 2024

Exploring Structural Requirements for Sigma-1 Receptor Linear Ligands: Experimental and Computational Approaches.

Exploring Structural Requirements for Sigma-1 Receptor Linear Ligands: Experimental and Computational Approaches.

Journal: Journal of chemical information and modeling

Published: June 28, 2024

Novel sigma 1-antagonists with cis-(+)-normetazocine scaffold: synthesis, molecular modeling, and antinociceptive effect.

Novel sigma 1-antagonists with cis-(+)-normetazocine scaffold: synthesis, molecular modeling, and antinociceptive effect.

Journal: RSC medicinal chemistry

Published: May 30, 2024

Mechanisms of the Antineoplastic Effects of New Fluoroquinolones in 2D and 3D Human Breast and Bladder Cancer Cell Lines.

Mechanisms of the Antineoplastic Effects of New Fluoroquinolones in 2D and 3D Human Breast and Bladder Cancer Cell Lines.

Journal: Cancers

Published: May 08, 2024

Showing 1-12 of 96

Last Updated: 09/26/2026