Ahmed F. Sayed-El

Giza, GZ, Egypt

Last Updated: 09/26/2026

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Found 48 publications

Design and Synthesis of Novel Morpholine-Derived Nitrogen-Rich Scaffolds as Multifunctional Anticancer and Antibacterial Agents: Biological Evaluation and Computational Studies.

Design and Synthesis of Novel Morpholine-Derived Nitrogen-Rich Scaffolds as Multifunctional Anticancer and Antibacterial Agents: Biological Evaluation and Computational Studies.

Journal: Pharmaceutics
Published: July 21, 2026

Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as promising antioxidant and antimicrobial agents: Synthesis, antibiofilm, DFT calculations, molecular docking, ADMET analysis, and MD simulations.

Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as promising antioxidant and antimicrobial agents: Synthesis, antibiofilm, DFT calculations, molecular docking, ADMET analysis, and MD simulations.

Journal: Bioorganic chemistry
Published: June 14, 2026

Green NiO nanoparticle catalyzed synthesis of novel triazolopyrimidine derivatives with physicochemical characterization and computational evaluation for gout therapy.

Green NiO nanoparticle catalyzed synthesis of novel triazolopyrimidine derivatives with physicochemical characterization and computational evaluation for gout therapy.

Journal: Scientific reports
Published: February 27, 2026

From Synthesis to Mechanism: Biological Evaluation of a p-Toluidine-Based Thiazolidinone-Quinoline VEGFR-2 Candidate Supported by CADD.

From Synthesis to Mechanism: Biological Evaluation of a p-Toluidine-Based Thiazolidinone-Quinoline VEGFR-2 Candidate Supported by CADD.

Journal: International journal of molecular sciences
Published: February 15, 2026

Unveiling the antibacterial potential of green-synthesized silver chloride and silver chromium nanoparticles from Pelargonium graveolens extract through molecular docking and bioactivity studies.

Unveiling the antibacterial potential of green-synthesized silver chloride and silver chromium nanoparticles from Pelargonium graveolens extract through molecular docking and bioactivity studies.

Journal: Microbiology spectrum
Published: November 25, 2025

Design, characterization, DFT studies, and molecular docking of new benzofuran-pyrazol-acrylamide hybrids as insecticidal agents against Spodoptera littoralis and Tribolium castaneum.

Design, characterization, DFT studies, and molecular docking of new benzofuran-pyrazol-acrylamide hybrids as insecticidal agents against Spodoptera littoralis and Tribolium castaneum.

Journal: Scientific reports
Published: November 10, 2025

Superiority of Chrysophyllum oliviforme in the green synthesis of highly stable ZnO nanoparticles: metabolomic profiling, quadruple antiviral screening, and comparative MD simulations.

Superiority of Chrysophyllum oliviforme in the green synthesis of highly stable ZnO nanoparticles: metabolomic profiling, quadruple antiviral screening, and comparative MD simulations.

Journal: Discover nano
Published: November 03, 2025

Therapeutic potential of nicorandil vs nebivolol in attenuating PKC/P38MAPK signaling via PPARγ/KLOTHO/CREB pathway signaling: molecular docking and experimental validation in rat model of unilateral ureteric obstruction.

Therapeutic potential of nicorandil vs nebivolol in attenuating PKC/P38MAPK signaling via PPARγ/KLOTHO/CREB pathway signaling: molecular docking and experimental validation in rat model of unilateral ureteric obstruction.

Journal: European journal of pharmacology
Published: October 03, 2025

Enhanced antibacterial and antioxidant capabilities using indole-modified 1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile derivatives, molecular docking evaluation and in silico ADMET prediction.

Enhanced antibacterial and antioxidant capabilities using indole-modified 1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile derivatives, molecular docking evaluation and in silico ADMET prediction.

Journal: RSC advances
Published: September 28, 2025

In Vivo Therapeutic Potential of Biologically Synthesized Nanoparticles From Pine Needle Leaf Extract in Streptozotocin-Induced Diabetic Rats.

In Vivo Therapeutic Potential of Biologically Synthesized Nanoparticles From Pine Needle Leaf Extract in Streptozotocin-Induced Diabetic Rats.

Journal: BioMed research international
Published: September 17, 2025

Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway.

Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway.

Journal: Inflammopharmacology
Published: September 11, 2025

Synthesis, molecular docking, ADMET studies and biological evaluation of fused pyrazolopyridopyrimidine derivatives as antioxidant and antimicrobial agents.

Synthesis, molecular docking, ADMET studies and biological evaluation of fused pyrazolopyridopyrimidine derivatives as antioxidant and antimicrobial agents.

Journal: Scientific reports
Published: August 27, 2025
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Last Updated: 09/26/2026