Akira Nakai

Ube, Japan

Last Updated: 09/26/2026

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Found 48 publications

HSF1/HSP25 system protects mitochondria function from heat stress and assists steroidogenesis in MA-10 Leydig cells.

HSF1/HSP25 system protects mitochondria function from heat stress and assists steroidogenesis in MA-10 Leydig cells.

Journal: Molecular and cellular endocrinology
Published: June 11, 2024

HSF1 is required for cellular adaptation to daily temperature fluctuations.

HSF1 is required for cellular adaptation to daily temperature fluctuations.

Journal: Scientific reports
Published: May 21, 2024

Regulation of HSF1 transcriptional complexes under proteotoxic stress: Mechanisms of heat shock gene transcription involve the stress-induced HSF1 complex formation, changes in chromatin states, and formation of phase-separated condensates: Mechanisms of heat shock gene transcription involve the stress-induced HSF1 complex formation, changes in chromatin states, and formation of phase-separated condensates.

Regulation of HSF1 transcriptional complexes under proteotoxic stress: Mechanisms of heat shock gene transcription involve the stress-induced HSF1 complex formation, changes in chromatin states, and formation of phase-separated condensates: Mechanisms of heat shock gene transcription involve the stress-induced HSF1 complex formation, changes in chromatin states, and formation of phase-separated condensates.

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology
Published: February 19, 2023

The Mediator subunit MED12 promotes formation of HSF1 condensates on heat shock response element arrays in heat-shocked cells.

The Mediator subunit MED12 promotes formation of HSF1 condensates on heat shock response element arrays in heat-shocked cells.

Journal: FEBS letters
Published: December 28, 2022

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

Journal: Nature communications
Published: March 31, 2022

Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response.

Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response.

Journal: Life science alliance
Published: September 22, 2021

MED12 interacts with the heat-shock transcription factor HSF1 and recruits CDK8 to promote the heat-shock response in mammalian cells.

MED12 interacts with the heat-shock transcription factor HSF1 and recruits CDK8 to promote the heat-shock response in mammalian cells.

Journal: FEBS letters
Published: January 25, 2021

Testicular localization of activating transcription factor 1 and its potential function during spermatogenesis†.

Testicular localization of activating transcription factor 1 and its potential function during spermatogenesis†.

Journal: Biology of reproduction
Published: December 09, 2020

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS-mitochondrial fission-mitophagy axis.

Journal: Molecular oncology
Published: August 27, 2020

Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.

Nuciferine protects against folic acid-induced acute kidney injury by inhibiting ferroptosis.

Journal: British journal of pharmacology
Published: April 07, 2020

HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response.

HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response.

Journal: FEBS open bio
Published: November 26, 2019

The pericentromeric protein shugoshin 2 cooperates with HSF1 in heat shock response and RNA Pol II recruitment.

The pericentromeric protein shugoshin 2 cooperates with HSF1 in heat shock response and RNA Pol II recruitment.

Journal: The EMBO journal
Published: May 29, 2019
Showing 1-12 of 48

Last Updated: 09/26/2026