Akira Ooka

Shizuoka, Japan

Last Updated: 09/26/2026

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Found 11 publications

Ordinal association between cytochrome P450 inhibition and hepatotoxicity severity in rats.

Ordinal association between cytochrome P450 inhibition and hepatotoxicity severity in rats.

Journal: The Journal of toxicological sciences

Published: May 06, 2026

Read-across prediction of nongenotoxic thyroid carcinogenicity of pesticides in rats using mechanism-based in vitro assay data.

Read-across prediction of nongenotoxic thyroid carcinogenicity of pesticides in rats using mechanism-based in vitro assay data.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: September 05, 2025

Cytochrome P450 inhibition correlates with hepatotoxicity of pesticides: Analysis using repeated-dose toxicity data in rats.

Cytochrome P450 inhibition correlates with hepatotoxicity of pesticides: Analysis using repeated-dose toxicity data in rats.

Journal: Drug metabolism and pharmacokinetics

Published: July 07, 2025

Machine Learning on Toxicogenomic Data Reveals a Strong Association Between the Induction of Drug-Metabolizing Enzymes and Centrilobular Hepatocyte Hypertrophy in Rats.

Machine Learning on Toxicogenomic Data Reveals a Strong Association Between the Induction of Drug-Metabolizing Enzymes and Centrilobular Hepatocyte Hypertrophy in Rats.

Journal: International journal of molecular sciences

Published: March 12, 2025

Differentiation-inducing factor-1 ameliorates liver fibrosis through the reversion of activated hepatic stellate cells.

Differentiation-inducing factor-1 ameliorates liver fibrosis through the reversion of activated hepatic stellate cells.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: November 28, 2024

Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression.

Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression.

Journal: The Biochemical journal

Published: April 14, 2024

Effects of phospholipid type and particle size on lipid nanoparticle distribution in vivo and in pancreatic islets.

Effects of phospholipid type and particle size on lipid nanoparticle distribution in vivo and in pancreatic islets.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: March 15, 2024

Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice.

Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice.

Journal: Scientific reports

Published: December 23, 2022

Harmine suppresses collagen production in hepatic stellate cells by inhibiting DYRK1B.

Harmine suppresses collagen production in hepatic stellate cells by inhibiting DYRK1B.

Journal: Biochemical and biophysical research communications

Published: February 15, 2022

Caffeine-induced inversion of prostaglandin E2 effects on hepatic stellate cell activation.

Caffeine-induced inversion of prostaglandin E2 effects on hepatic stellate cell activation.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: July 02, 2021

Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation.

Differentiation-inducing factor-1 prevents hepatic stellate cell activation through inhibiting GSK3β inactivation.

Journal: Biochemical and biophysical research communications

Published: September 12, 2019

Showing 1-11 of 11

Last Updated: 09/26/2026