Akito Kawai

Toyoake, Japan

Last Updated: 09/26/2026

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Found 20 publications

A Val292 substitution combined with an alanine duplication (ADUP) in the Ω loop of ADC β-lactamase confers reduced susceptibility to advanced β-lactam agents, including cefiderocol.

A Val292 substitution combined with an alanine duplication (ADUP) in the Ω loop of ADC β-lactamase confers reduced susceptibility to advanced β-lactam agents, including cefiderocol.

Journal: mBio
Published: April 08, 2026

In vitro evolution of durlobactam resistance in NDM-producing Escherichia coli due to a single mutation in mrdA encoding penicillin-binding protein 2.

In vitro evolution of durlobactam resistance in NDM-producing Escherichia coli due to a single mutation in mrdA encoding penicillin-binding protein 2.

Journal: Antimicrobial agents and chemotherapy
Published: October 10, 2025

Insights into Dual Binding Modes of Nateglinide to Human Serum Albumin.

Insights into Dual Binding Modes of Nateglinide to Human Serum Albumin.

Journal: ACS medicinal chemistry letters
Published: May 06, 2025

Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.

Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.

Journal: Journal of medicinal chemistry
Published: July 31, 2024

Clinical and molecular landscape of prolonged SARS-CoV-2 infection with resistance to remdesivir in immunocompromised patients.

Clinical and molecular landscape of prolonged SARS-CoV-2 infection with resistance to remdesivir in immunocompromised patients.

Journal: PNAS nexus
Published: June 17, 2024

Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185.

Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185.

Journal: mBio
Published: January 05, 2024

High-level ceftazidime-avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated beta-lactamase CMY-185 variant.

High-level ceftazidime-avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated beta-lactamase CMY-185 variant.

Journal: bioRxiv : the preprint server for biology
Published: February 13, 2023

High-level ceftazidime/avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated β-lactamase CMY-185 variant.

High-level ceftazidime/avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated β-lactamase CMY-185 variant.

Journal: The Journal of antimicrobial chemotherapy
Published: February 07, 2023

Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure.

Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure.

Journal: Journal of medicinal chemistry
Published: December 20, 2022

Functional and Structural Characterization of Acquired 16S rRNA Methyltransferase NpmB1 Conferring Pan-Aminoglycoside Resistance.

Functional and Structural Characterization of Acquired 16S rRNA Methyltransferase NpmB1 Conferring Pan-Aminoglycoside Resistance.

Journal: Antimicrobial agents and chemotherapy
Published: July 26, 2021

Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions.

Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions.

Journal: Molecular pharmaceutics
Published: January 22, 2021

The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis.

The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis.

Journal: Nature communications
Published: February 27, 2020
Showing 1-12 of 20

Last Updated: 09/26/2026