Akitsu Hotta

Fujisawa, Japan

Last Updated: 09/26/2026

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Found 86 publications

SLF2 and SMC5 dysfunction drives HSC aging and predisposes to MDS, defining a new inherited bone marrow failure syndrome.

SLF2 and SMC5 dysfunction drives HSC aging and predisposes to MDS, defining a new inherited bone marrow failure syndrome.

Journal: Leukemia
Published: February 05, 2026

Comprehensive assessment of on- and off-target mutagenesis via lipid nanoparticle delivery of CRISPR-Cas9 genome editing.

Comprehensive assessment of on- and off-target mutagenesis via lipid nanoparticle delivery of CRISPR-Cas9 genome editing.

Journal: Molecular therapy. Nucleic acids
Published: October 05, 2025

Muscle satellite cell editing by LNP-CRISPR-Cas9 to resist muscle injury.

Muscle satellite cell editing by LNP-CRISPR-Cas9 to resist muscle injury.

Journal: Cell reports
Published: September 08, 2025

Human iPSC-derived engineered heart tissue model of diastolic dysfunction in heart failure with preserved ejection fraction.

Human iPSC-derived engineered heart tissue model of diastolic dysfunction in heart failure with preserved ejection fraction.

Journal: Cell stem cell
Published: July 28, 2025

Report on the rare disease consortium Japan inaugural symposium - July 18, 2023, shonan health innovation park, Japan.

Report on the rare disease consortium Japan inaugural symposium - July 18, 2023, shonan health innovation park, Japan.

Journal: Journal of neuromuscular diseases
Published: July 23, 2025

SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike protein.

SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike protein.

Journal: Biomaterials
Published: April 05, 2025

Combined rapamycin and mesenchymal stem/stromal cells derived from induced pluripotent stem cells-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva.

Combined rapamycin and mesenchymal stem/stromal cells derived from induced pluripotent stem cells-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva.

Journal: JBMR plus
Published: January 13, 2025

An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification.

An iPSC-based in vitro model recapitulates human thymic epithelial development and multi-lineage specification.

Journal: Nature communications
Published: October 21, 2024

Diversifying the reference iPSC line concept.

Diversifying the reference iPSC line concept.

Journal: Cell stem cell
Published: September 03, 2024

Optimized simple culture protocol for inducing mature myotubes from MYOD1-overexpressed human iPS cells.

Optimized simple culture protocol for inducing mature myotubes from MYOD1-overexpressed human iPS cells.

Journal: Scientific reports
Published: July 30, 2024

Elimination of the extra chromosome of Dup15q syndrome iPSCs for cellular and molecular investigation.

Elimination of the extra chromosome of Dup15q syndrome iPSCs for cellular and molecular investigation.

Journal: European journal of cell biology
Published: April 17, 2024

AMPK-p38 axis converts human pluripotent stem cells to naive state.

AMPK-p38 axis converts human pluripotent stem cells to naive state.

Journal: iScience
Published: January 05, 2024
Showing 1-12 of 86

Last Updated: 09/26/2026