Alain Bruhat

Clermont-ferrand, 63000, France

Last Updated: 09/26/2026

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Found 31 publications

The GCN2-ATF4 signaling axis orchestrates the hepatic transcriptional stress response to short-term sulfur amino acid deprivation.

The GCN2-ATF4 signaling axis orchestrates the hepatic transcriptional stress response to short-term sulfur amino acid deprivation.

Journal: Journal of molecular biology

Published: July 10, 2026

Transcriptomic analysis of human primary T cells after short-term leucine-deprivation and evaluation of kinase GCN2's role in regulating differential gene expression.

Transcriptomic analysis of human primary T cells after short-term leucine-deprivation and evaluation of kinase GCN2's role in regulating differential gene expression.

Journal: PloS one

Published: October 14, 2024

Identification of a specific set of genes predicting obesity before phenotype appearance.

Identification of a specific set of genes predicting obesity before phenotype appearance.

Journal: iScience

Published: July 17, 2024

Pre-cachectic changes in amino acid homeostasis precede activation of eIF2α signaling in the liver at the onset of C26 cancer-induced cachexia.

Pre-cachectic changes in amino acid homeostasis precede activation of eIF2α signaling in the liver at the onset of C26 cancer-induced cachexia.

Journal: iScience

Published: March 04, 2024

Temporal regulation of transgene expression controlled by amino acid availability in human T cells.

Temporal regulation of transgene expression controlled by amino acid availability in human T cells.

Journal: HLA

Published: May 03, 2023

Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears.

Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears.

Journal: International journal of molecular sciences

Published: October 14, 2022

Activation of the eIF2α-ATF4 Pathway by Chronic Paracetamol Treatment Is Prevented by Dietary Supplementation with Cysteine.

Activation of the eIF2α-ATF4 Pathway by Chronic Paracetamol Treatment Is Prevented by Dietary Supplementation with Cysteine.

Journal: International journal of molecular sciences

Published: May 24, 2022

GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid.

GCN2 upregulates autophagy in response to short-term deprivation of a single essential amino acid.

Journal: Autophagy reports

Published: April 07, 2022

When idiopathic male infertility is rooted in maternal malnutrition during the perinatal period in mice†.

When idiopathic male infertility is rooted in maternal malnutrition during the perinatal period in mice†.

Journal: Biology of reproduction

Published: July 22, 2021

Complex Mechanisms Link Dietary Sulfur Amino Acid Restriction to Health Improvement.

Complex Mechanisms Link Dietary Sulfur Amino Acid Restriction to Health Improvement.

Journal: The Journal of nutrition

Published: December 15, 2020

HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis.

HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis.

Journal: Scientific reports

Published: August 07, 2018

The CCAAT/enhancer-binding protein-ATF response elements-luciferase mouse model, an innovative tool to monitor the integrated stress response pathway in vivo.

The CCAAT/enhancer-binding protein-ATF response elements-luciferase mouse model, an innovative tool to monitor the integrated stress response pathway in vivo.

Journal: Current opinion in clinical nutrition and metabolic care

Published: April 05, 2017

Showing 1-12 of 31

Last Updated: 09/26/2026