Alain Opakua-De

Goettingen, NI 37075, Germany

Last Updated: 09/26/2026

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Found 25 publications

Metabolomic-based aging clocks.

Metabolomic-based aging clocks.

Journal: npj metabolic health and disease

Published: May 16, 2025

GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments.

GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 18, 2024

Integrated NMR-crystallography-computational approach for molecular recognition studies of human Gαi3 protein by a small molecule inhibitor.

Integrated NMR-crystallography-computational approach for molecular recognition studies of human Gαi3 protein by a small molecule inhibitor.

Journal: International journal of biological macromolecules

Published: October 16, 2024

Multimodal interactions drive chromatin phase separation and compaction.

Multimodal interactions drive chromatin phase separation and compaction.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 04, 2023

Impact of distinct FG nucleoporin repeats on Nup98 self-association.

Impact of distinct FG nucleoporin repeats on Nup98 self-association.

Journal: Nature communications

Published: June 15, 2023

Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer.

Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 25, 2023

Determining the Physico-Chemical Composition of Biomolecular Condensates from Spatially-Resolved NMR.

Determining the Physico-Chemical Composition of Biomolecular Condensates from Spatially-Resolved NMR.

Journal: Angewandte Chemie (International ed. in English)

Published: December 07, 2022

A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity.

A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity.

Journal: Science advances

Published: April 29, 2022

Contributions of the N-terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA-induced phase separation.

Contributions of the N-terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA-induced phase separation.

Journal: Protein science : a publication of the Protein Society

Published: March 30, 2022

Molecular interactions of FG nucleoporin repeats at high resolution.

Molecular interactions of FG nucleoporin repeats at high resolution.

Journal: Nature chemistry

Published: February 07, 2022

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage.

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage.

Journal: Nature communications

Published: December 27, 2021

Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding.

Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding.

Journal: Molecular cell

Published: December 08, 2021

Showing 1-12 of 25

Last Updated: 09/26/2026