Alain Pierre
Croissy-sur-seine, 78290, France
Last Updated: 09/26/2026
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Found 44 publications
Synthesis, antitumor activity, and mechanism of action of benzo[b]chromeno[6,5-g][1,8]naphthyridin-7-one analogs of acronycine.
Journal: Journal of medicinal chemistry
Published: November 01, 2014
TIPIN depletion leads to apoptosis in breast cancer cells.
Journal: Molecular oncology
Published: October 23, 2014
Radiosensitization by a novel Bcl-2 and Bcl-XL inhibitor S44563 in small-cell lung cancer.
Journal: Cell death & disease
Published: March 31, 2014
Targeting Bcl-2/Bcl-XL induces antitumor activity in uveal melanoma patient-derived xenografts.
Journal: PloS one
Published: September 04, 2013
S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Journal: Molecular cancer therapeutics
Published: June 28, 2013
Polo-like kinase 1: a potential therapeutic option in combination with conventional chemotherapy for the management of patients with triple-negative breast cancer.
Journal: Cancer research
Published: November 13, 2012
TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer.
Journal: PloS one
Published: November 08, 2012
Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 25, 2012
Novel protein scaffolds as emerging therapeutic proteins: from discovery to clinical proof-of-concept.
Journal: Trends in biotechnology
Published: April 18, 2012
Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.
Journal: Life sciences
Published: February 04, 2011
Synthesis and cytotoxic activity of benzo[a]acronycine and benzo[b]acronycine substituted on the A ring.
Journal: European journal of medicinal chemistry
Published: January 11, 2011
Influence of the stereoisomeric position of the reactive acetate groups of the benzo[b]acronycine derivative S23906-1 on its DNA alkylation, helix-opening, cytotoxic, and antitumor activities.
Journal: Molecular pharmacology
Published: September 16, 2009
Last Updated: 09/26/2026