Alan A. Melcher

Fulham Road
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 149 publications

Engagement of the TCR against an oncolytic virus generates a population of effector CAR T cells with potent antitumor activity.

Engagement of the TCR against an oncolytic virus generates a population of effector CAR T cells with potent antitumor activity.

Journal: Science advances

Published: June 05, 2026

Effects of oncolytic immunotherapy with RP1 (vusolimogene oderparepvec) on immune cells mediate responsiveness to anti-PD-1 via STING-mediated interferon signaling.

Effects of oncolytic immunotherapy with RP1 (vusolimogene oderparepvec) on immune cells mediate responsiveness to anti-PD-1 via STING-mediated interferon signaling.

Journal: Journal for immunotherapy of cancer

Published: February 07, 2026

Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome.

Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome.

Journal: Cancer immunology research

Published: December 11, 2025

Xevinapant plus Chemoradiotherapy Negatively Sculpts the Tumor-Immune Microenvironment in Head and Neck Cancer.

Xevinapant plus Chemoradiotherapy Negatively Sculpts the Tumor-Immune Microenvironment in Head and Neck Cancer.

Journal: Cancer research communications

Published: October 02, 2025

Addition of oncolytic virotherapy to clinical isolated limb perfusion for melanoma and sarcoma activates antitumor immunity.

Addition of oncolytic virotherapy to clinical isolated limb perfusion for melanoma and sarcoma activates antitumor immunity.

Journal: Journal for immunotherapy of cancer

Published: August 27, 2025

PD-L1 Immuno-PET Reveals Systemic Effects of Localized Oncolytic Virotherapy in a Mouse Model of Head and Neck Cancer.

PD-L1 Immuno-PET Reveals Systemic Effects of Localized Oncolytic Virotherapy in a Mouse Model of Head and Neck Cancer.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Published: August 03, 2025

Author Correction: Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion.

Author Correction: Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion.

Journal: Nature communications

Published: July 15, 2025

Modulating T-cell Responses to Enhance the Effects of Radiotherapy.

Modulating T-cell Responses to Enhance the Effects of Radiotherapy.

Journal: Cancer journal (Sudbury, Mass.)

Published: May 13, 2025

The untapped potential of radiation and immunotherapy for hormone receptor-positive breast cancer.

The untapped potential of radiation and immunotherapy for hormone receptor-positive breast cancer.

Journal: NPJ breast cancer

Published: April 17, 2025

Corrigendum: Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment.

Corrigendum: Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment.

Journal: Frontiers in immunology

Published: March 27, 2025

Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma.

Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma.

Journal: International journal of cancer

Published: January 28, 2025

Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy.

Necroptosis in both tumour and stromal compartments determines responsiveness to immunogenic cell death-based immunotherapy.

Journal: Nature communications

Published: January 08, 2025

Showing 1-12 of 149

Last Updated: 09/26/2026