Alan D. Brown

Francis Crick Avenue
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 47 publications

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.

Journal: Science advances

Published: December 06, 2024

Dual Kv7.2/3-TRPV1 modulators inhibit nociceptor hyperexcitability and alleviate pain without target-related side effects.

Dual Kv7.2/3-TRPV1 modulators inhibit nociceptor hyperexcitability and alleviate pain without target-related side effects.

Journal: Pain

Published: April 09, 2024

Parental orders for deceased intended parents: Re X (Foreign Surrogacy: Death of Intended Parent) [2022] EWFC 34.

Parental orders for deceased intended parents: Re X (Foreign Surrogacy: Death of Intended Parent) [2022] EWFC 34.

Journal: Medical law review

Published: November 17, 2022

Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.

Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes.

Journal: eLife

Published: July 04, 2022

Trans Parenthood and the Meaning of 'Mother', 'Father' and 'Parent'-R (McConnell and YY) v Registrar General for England and Wales [2020] EWCA Civ 559.

Trans Parenthood and the Meaning of 'Mother', 'Father' and 'Parent'-R (McConnell and YY) v Registrar General for England and Wales [2020] EWCA Civ 559.

Journal: Medical law review

Published: March 15, 2021

DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity.

DNA methylation across the genome in aged human skeletal muscle tissue and muscle-derived cells: the role of HOX genes and physical activity.

Journal: Scientific reports

Published: June 01, 2020

Incidence and characteristics of pregnancy-related death across ten low- and middle-income geographical regions: secondary analysis of a cluster randomised controlled trial.

Incidence and characteristics of pregnancy-related death across ten low- and middle-income geographical regions: secondary analysis of a cluster randomised controlled trial.

Journal: BJOG : an international journal of obstetrics and gynaecology

Published: April 22, 2020

The discovery and optimization of benzimidazoles as selective NaV1.8 blockers for the treatment of pain.

The discovery and optimization of benzimidazoles as selective NaV1.8 blockers for the treatment of pain.

Journal: Bioorganic & medicinal chemistry

Published: August 22, 2018

Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes.

Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes.

Journal: Bioorganic & medicinal chemistry letters

Published: July 22, 2017

Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.

Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.

Journal: Journal of medicinal chemistry

Published: July 07, 2017

Structures of the human mitochondrial ribosome in native states of assembly.

Structures of the human mitochondrial ribosome in native states of assembly.

Journal: Nature structural & molecular biology

Published: June 09, 2017

The structure of the yeast mitochondrial ribosome.

The structure of the yeast mitochondrial ribosome.

Journal: Science (New York, N.Y.)

Published: October 18, 2016

Showing 1-12 of 47

Last Updated: 09/26/2026