Alan M. Holmes
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 14 publications
Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds.
Journal: Frontiers in toxicology
Published: June 27, 2025
Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension.
Journal: The international journal of biochemistry & cell biology
Published: September 11, 2020
Platelet-derived transforming growth factor-β1 promotes keratinocyte proliferation in cutaneous wound healing.
Journal: Journal of tissue engineering and regenerative medicine
Published: April 15, 2019
Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells.
Journal: eLife
Published: July 07, 2017
Does age matter? The impact of rodent age on study outcomes.
Journal: Laboratory animals
Published: June 17, 2016
Impaired bone morphogenetic protein receptor II signaling in a transforming growth factor-β-dependent mouse model of pulmonary hypertension and in systemic sclerosis.
Journal: American journal of respiratory and critical care medicine
Published: January 22, 2015
Endothelial to Mesenchymal Transition Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension.
Journal: The American journal of pathology
Published: July 29, 2014
Failed degradation of JunB contributes to overproduction of type I collagen and development of dermal fibrosis in patients with systemic sclerosis.
Journal: Arthritis & rheumatology (Hoboken, N.J.)
Published: January 14, 2014
Evidence for the involvement of type I interferon in pulmonary arterial hypertension.
Journal: Circulation research
Published: December 17, 2013
Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells.
Journal: Arthritis research & therapy
Published: June 26, 2013
Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.
Journal: The American journal of pathology
Published: November 26, 2012
Endothelial injury in a transforming growth factor β-dependent mouse model of scleroderma induces pulmonary arterial hypertension.
Journal: Arthritis and rheumatism
Published: October 03, 2012
Last Updated: 09/26/2026