Alan M. Kennedy
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 55 publications
An imbalance between CD80 and CD86 levels and CD4 regulatory T cell number and transendocytosis function exists in the liver in autoimmune hepatitis.
Journal: Clinical and experimental immunology
Published: July 24, 2025
Immune dysregulation from a novel CTLA-4 haploinsufficiency variant.
Journal: Journal of human immunity
Published: June 07, 2025
Are single-lead consumer ECG devices enough for accurate QTc monitoring? A calibrated uncertainty AI approach.
Journal: Journal of electrocardiology
Published: May 14, 2025
High affinity is insufficient for strong B cell activation by HIV broadly neutralising antibodies.
Journal: NPJ vaccines
Published: April 24, 2025
CD28 and TCR differentially impact naïve and memory T cell responses.
Journal: Discovery immunology
Published: December 16, 2024
Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction.
Journal: Cell reports
Published: May 09, 2024
Precordial electrocardiographic recording and QT measurement from a novel wearable ring device.
Journal: Cardiovascular digital health journal
Published: February 23, 2024
Reducing the burden of inconclusive smart device single-lead ECG tracings via a novel artificial intelligence algorithm.
Journal: Cardiovascular digital health journal
Published: February 23, 2024
Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 24, 2023
Therapeutic gene editing of T cells to correct CTLA-4 insufficiency.
Journal: Science translational medicine
Published: October 26, 2022
In Vitro Analysis of CTLA-4-Mediated Transendocytosis by Regulatory T Cells.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: September 30, 2022
Last Updated: 09/26/2026