Alastair S. Garfield

Bath, ENG BA27AY, United Kingdom

Last Updated: 09/26/2026

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Found 31 publications

An ABCB11 variant registry and novel knockin mouse model of PFIC2 based on the clinically relevant ABCB11 E297G variant.

An ABCB11 variant registry and novel knockin mouse model of PFIC2 based on the clinically relevant ABCB11 E297G variant.

Journal: Journal of lipid research
Published: October 17, 2024

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism.

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism.

Journal: BMC biology
Published: February 02, 2024

Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes.

Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes.

Journal: BMC biology
Published: November 21, 2023

ABC transporters: human disease and pharmacotherapeutic potential.

ABC transporters: human disease and pharmacotherapeutic potential.

Journal: Trends in molecular medicine
Published: August 30, 2022

Food cue regulation of AGRP hunger neurons guides learning.

Food cue regulation of AGRP hunger neurons guides learning.

Journal: Nature
Published: November 13, 2019

Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells.

Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells.

Journal: Endocrinology
Published: October 08, 2019

Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation.

Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation.

Journal: Molecules (Basel, Switzerland)
Published: April 21, 2019

The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits.

The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits.

Journal: Neuron
Published: December 22, 2018

Tracing the effect of the melanocortin-4 receptor pathway in obesity: study design and methodology of the TEMPO registry.

Tracing the effect of the melanocortin-4 receptor pathway in obesity: study design and methodology of the TEMPO registry.

Journal: The application of clinical genetics
Published: December 21, 2018

Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.

Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment.

Journal: The Journal of clinical endocrinology and metabolism
Published: January 31, 2018

Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite.

Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite.

Journal: Molecular brain
Published: May 25, 2016

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons.

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons.

Journal: Molecular metabolism
Published: December 12, 2015
Showing 1-12 of 31

Last Updated: 09/26/2026