Alberto Bresciani

IRBM Science Park
Rome, Italy

Last Updated: 09/26/2026

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Found 48 publications

In silico screening and preclinical validation identify bavisant as a therapeutic candidate for multiple sclerosis.

In silico screening and preclinical validation identify bavisant as a therapeutic candidate for multiple sclerosis.

Journal: Science translational medicine

Published: January 21, 2026

An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models.

An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models.

Journal: Nature communications

Published: May 15, 2025

Optimization of Single Relaxin B-Chain Peptide Leads to the Identification of R2R01, a Potent, Long-Acting RXFP1 Agonist for Cardiovascular and Renal Diseases.

Optimization of Single Relaxin B-Chain Peptide Leads to the Identification of R2R01, a Potent, Long-Acting RXFP1 Agonist for Cardiovascular and Renal Diseases.

Journal: Journal of medicinal chemistry

Published: January 31, 2025

Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.

Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.

Journal: Journal of medicinal chemistry

Published: September 15, 2023

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.

A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.

Journal: Virology

Published: December 26, 2022

Salivary Huntingtin protein is uniquely associated with clinical features of Huntington's disease.

Salivary Huntingtin protein is uniquely associated with clinical features of Huntington's disease.

Journal: Scientific reports

Published: August 17, 2022

Quantifying Huntingtin Protein in Human Cerebrospinal Fluid Using a Novel Polyglutamine Length-Independent Assay.

Quantifying Huntingtin Protein in Human Cerebrospinal Fluid Using a Novel Polyglutamine Length-Independent Assay.

Journal: Journal of Huntington's disease

Published: August 08, 2022

Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases.

Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases.

Journal: Life sciences

Published: August 01, 2022

Identification and in vitro characterization of a new series of potent and highly selective G9a inhibitors as novel anti-fibroadipogenic agents.

Identification and in vitro characterization of a new series of potent and highly selective G9a inhibitors as novel anti-fibroadipogenic agents.

Journal: Bioorganic & medicinal chemistry letters

Published: February 10, 2022

Gametocyte-specific and all-blood-stage transmission-blocking chemotypes discovered from high throughput screening on Plasmodium falciparum gametocytes.

Gametocyte-specific and all-blood-stage transmission-blocking chemotypes discovered from high throughput screening on Plasmodium falciparum gametocytes.

Journal: Communications biology

Published: February 09, 2022

AAV5-miHTT-mediated huntingtin lowering improves brain health in a Huntington's disease mouse model.

AAV5-miHTT-mediated huntingtin lowering improves brain health in a Huntington's disease mouse model.

Journal: Brain : a journal of neurology

Published: January 28, 2022

SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease.

SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease.

Journal: Bioorganic & medicinal chemistry

Published: July 30, 2021

Showing 1-12 of 48

Last Updated: 09/26/2026