Aleksandra A. Czyrek

Wroclaw, DS 50383, Poland

Last Updated: 09/26/2026

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Found 24 publications

Structure-function relationship in FGF signaling: rational design of highly stable FGF2 variants and their effect on cell growth, metabolism, and survival.

Structure-function relationship in FGF signaling: rational design of highly stable FGF2 variants and their effect on cell growth, metabolism, and survival.

Journal: Journal of biological engineering

Published: February 03, 2026

Infigratinib is a weak inhibitor of the FGFR3-N540K mutant associated with hypochondroplasia.

Infigratinib is a weak inhibitor of the FGFR3-N540K mutant associated with hypochondroplasia.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Published: August 22, 2025

Engineered fibroblast growth factor 1 variants uncouple glucose-lowering effects from mitogenic activity with therapeutic potential for type 2 diabetes.

Engineered fibroblast growth factor 1 variants uncouple glucose-lowering effects from mitogenic activity with therapeutic potential for type 2 diabetes.

Journal: Molecular biomedicine

Published: July 20, 2025

Fibroblast Growth Factors in Lung Development and Regeneration: Mechanisms and Therapeutic Potential.

Fibroblast Growth Factors in Lung Development and Regeneration: Mechanisms and Therapeutic Potential.

Journal: Cells

Published: July 18, 2025

Oral Infigratinib Therapy in Children with Achondroplasia.

Oral Infigratinib Therapy in Children with Achondroplasia.

Journal: The New England journal of medicine

Published: June 18, 2025

Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors.

Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors.

Journal: Cell communication and signaling : CCS

Published: November 28, 2024

Increased thermal stability of FGF10 leads to ectopic signaling during development.

Increased thermal stability of FGF10 leads to ectopic signaling during development.

Journal: Cellular and molecular life sciences : CMLS

Published: August 21, 2024

Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.

Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Published: August 16, 2024

Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.

Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer.

Journal: Molecular therapy. Nucleic acids

Published: June 18, 2024

FGFR2 residence in primary cilia is necessary for epithelial cell signaling.

FGFR2 residence in primary cilia is necessary for epithelial cell signaling.

Journal: The Journal of cell biology

Published: November 07, 2023

Correction: Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling.

Correction: Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling.

Journal: Cell communication and signaling : CCS

Published: June 13, 2023

FGF1 Protects MCF-7 Cells against Taltobulin through Both the MEKs/ERKs and PI3K/AKT Signaling Pathway.

FGF1 Protects MCF-7 Cells against Taltobulin through Both the MEKs/ERKs and PI3K/AKT Signaling Pathway.

Journal: Biomedicines

Published: May 08, 2023

Showing 1-12 of 24

Last Updated: 09/26/2026