Ales Machara

Prague, PR, Czech Republic

Last Updated: 09/26/2026

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Found 25 publications

Identification of the trail-following pheromone receptor in termites.

Identification of the trail-following pheromone receptor in termites.

Journal: eLife

Published: August 19, 2025

Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study.

Investigating NFE2L1 activators for targeted protein aggregate clearance: a follow-up study.

Journal: RSC medicinal chemistry

Published: July 04, 2025

3'-Dehydroxypurpurogallin-4-Carboxamides as Influenza A Endonuclease Inhibitors: Synthesis, Structure-Activity Relationship Analysis, and Structural Characterization of Protein Complex.

3'-Dehydroxypurpurogallin-4-Carboxamides as Influenza A Endonuclease Inhibitors: Synthesis, Structure-Activity Relationship Analysis, and Structural Characterization of Protein Complex.

Journal: ChemMedChem

Published: July 03, 2025

Targeting NFE2L1 signalling with small molecules to protect against Ferroptosis.

Targeting NFE2L1 signalling with small molecules to protect against Ferroptosis.

Journal: Bioorganic & medicinal chemistry letters

Published: April 07, 2025

Beyond natural flavonoids: exploring bioisosterism in design and synthesis of influenza endonuclease inhibitors.

Beyond natural flavonoids: exploring bioisosterism in design and synthesis of influenza endonuclease inhibitors.

Journal: RSC medicinal chemistry

Published: January 22, 2025

Small-molecule activators of NRF1 transcriptional activity prevent protein aggregation.

Small-molecule activators of NRF1 transcriptional activity prevent protein aggregation.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: October 31, 2024

The evaluation of DNA-linked inhibitor antibody and AlphaScreen assays for high-throughput screening of compounds targeting the cap-binding domain in influenza a polymerase.

The evaluation of DNA-linked inhibitor antibody and AlphaScreen assays for high-throughput screening of compounds targeting the cap-binding domain in influenza a polymerase.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: October 27, 2024

Design, synthesis, and activity evaluation of C-8 arylated luteolin derivatives as influenza endonuclease inhibitors.

Design, synthesis, and activity evaluation of C-8 arylated luteolin derivatives as influenza endonuclease inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: September 17, 2024

3'-Dehydroxypurpurogallin-4-Carboxamides as Influenza A Endonuclease Inhibitors: Synthesis, Structure-Activity Relationship Analysis, and Structural Characterization of Protein Complex.

3'-Dehydroxypurpurogallin-4-Carboxamides as Influenza A Endonuclease Inhibitors: Synthesis, Structure-Activity Relationship Analysis, and Structural Characterization of Protein Complex.

Journal: ChemMedChem

Published: July 25, 2024

Evolution of Linoleic Acid Biosynthesis Paved the Way for Ecological Success of Termites.

Evolution of Linoleic Acid Biosynthesis Paved the Way for Ecological Success of Termites.

Journal: Molecular biology and evolution

Published: April 12, 2023

Characterization of Triacylglycerol Estolide Isomers Using High-Resolution Tandem Mass Spectrometry with Nanoelectrospray Ionization.

Characterization of Triacylglycerol Estolide Isomers Using High-Resolution Tandem Mass Spectrometry with Nanoelectrospray Ionization.

Journal: Biomolecules

Published: January 31, 2023

Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.

Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.

Journal: Antiviral research

Published: August 24, 2022

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Last Updated: 09/26/2026