Alessandra Silvani

Milan, Italy

Last Updated: 09/26/2026

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Found 48 publications

Synthesis of Sulfonamides in the Biobased Solvent Cyrene.

Synthesis of Sulfonamides in the Biobased Solvent Cyrene.

Journal: ChemistryOpen

Published: June 11, 2026

Mono- vs. Bis-Guanyl Hydrazone-Decorated Tricyclic Scaffolds: Effects on G-Quadruplex Binding and Selectivity.

Mono- vs. Bis-Guanyl Hydrazone-Decorated Tricyclic Scaffolds: Effects on G-Quadruplex Binding and Selectivity.

Journal: International journal of molecular sciences

Published: May 06, 2026

PROTAC-mediated degradation of peroxisomal d-aspartate oxidase: A novel strategy to modulate d-aspartate homeostasis for schizophrenia treatment.

PROTAC-mediated degradation of peroxisomal d-aspartate oxidase: A novel strategy to modulate d-aspartate homeostasis for schizophrenia treatment.

Journal: European journal of medicinal chemistry

Published: December 29, 2025

Structure-Based Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer.

Structure-Based Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer.

Journal: Journal of medicinal chemistry

Published: July 23, 2025

Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro and cathepsins for broad-spectrum anti-coronavirus activity.

Synthesis and multitarget inhibitory effect of indole-based ethyl cinnamate derivatives against SARS-CoV-2 Mpro and cathepsins for broad-spectrum anti-coronavirus activity.

Journal: Bioorganic & medicinal chemistry

Published: March 09, 2025

Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats.

Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats.

Journal: European journal of medicinal chemistry

Published: January 30, 2025

Sustainable Synthesis of 1,2,3-Triazoles using Cyrene as a Biodegradable Solvent in Click Chemistry.

Sustainable Synthesis of 1,2,3-Triazoles using Cyrene as a Biodegradable Solvent in Click Chemistry.

Journal: ChemSusChem

Published: November 27, 2024

Synthesis of α-fluorocinnamate derivatives as novel cathepsin S inhibitors with in vitro antiproliferative activity against pancreatic cancer cells.

Synthesis of α-fluorocinnamate derivatives as novel cathepsin S inhibitors with in vitro antiproliferative activity against pancreatic cancer cells.

Journal: Bioorganic & medicinal chemistry

Published: June 24, 2024

Nicotinic Acid Derivatives As Novel Noncompetitive α-Amylase and α-Glucosidase Inhibitors for Type 2 Diabetes Treatment.

Nicotinic Acid Derivatives As Novel Noncompetitive α-Amylase and α-Glucosidase Inhibitors for Type 2 Diabetes Treatment.

Journal: ACS medicinal chemistry letters

Published: April 25, 2024

PCSK9 inhibitors: a patent review 2018-2023.

PCSK9 inhibitors: a patent review 2018-2023.

Journal: Expert opinion on therapeutic patents

Published: April 08, 2024

Alkene carboamination/oxidative denitrogenation of 3-allyl-3-hydrazinylindolin-2-ones: one-pot entry to spirocyclopropyloxindoles.

Alkene carboamination/oxidative denitrogenation of 3-allyl-3-hydrazinylindolin-2-ones: one-pot entry to spirocyclopropyloxindoles.

Journal: Organic & biomolecular chemistry

Published: February 20, 2024

Computational Design, Synthesis, and Biological Evaluation of Diimidazole Analogues Endowed with Dual PCSK9/HMG-CoAR-Inhibiting Activity.

Computational Design, Synthesis, and Biological Evaluation of Diimidazole Analogues Endowed with Dual PCSK9/HMG-CoAR-Inhibiting Activity.

Journal: Journal of medicinal chemistry

Published: June 01, 2023

Showing 1-12 of 48

Last Updated: 09/26/2026