Alessandro Brigo
Basel, BS, Switzerland
Last Updated: 09/26/2026
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Found 19 publications
Preclinical pharmacology of alogabat: a novel GABAA-α5 positive allosteric modulator targeting neurodevelopmental disorders with impaired GABAA signaling.
Journal: Frontiers in pharmacology
Published: May 09, 2025
Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy.
Journal: Journal of medicinal chemistry
Published: March 18, 2025
SARM1 base-exchange inhibitors induce SARM1 activation and neurodegeneration at low doses.
Journal: npj drug discovery
Published: March 13, 2025
Federated Learning in Computational Toxicology: An Industrial Perspective on the Effiris Hackathon.
Journal: Chemical research in toxicology
Published: August 16, 2023
Assessing the utility of common arguments used in expert review of in silico predictions as part of ICH M7 assessments.
Journal: Regulatory toxicology and pharmacology : RTP
Published: May 15, 2023
Principles and Procedures for Assessment of Acute Toxicity Incorporating In Silico Methods.
Journal: Computational toxicology (Amsterdam, Netherlands)
Published: February 23, 2023
In Silico Approaches In Carcinogenicity Hazard Assessment: Current Status and Future Needs.
Journal: Computational toxicology (Amsterdam, Netherlands)
Published: April 04, 2022
Increasing the Value of Data Within a Large Pharmaceutical Company Through In Silico Models.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: February 21, 2022
Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 29, 2021
Skin sensitization in silico protocol.
Journal: Regulatory toxicology and pharmacology : RTP
Published: February 24, 2020
Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond.
Journal: Chemical research in toxicology
Published: December 21, 2019
Genetic toxicology in silico protocol.
Journal: Regulatory toxicology and pharmacology : RTP
Published: February 26, 2019
Last Updated: 09/26/2026