Alessandro Vacchini

Basel, BS 4031, Switzerland

Last Updated: 09/26/2026

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Found 23 publications

Expanding the MR1 ligandome using chemical class-specific fragmentation and molecular networking.

Expanding the MR1 ligandome using chemical class-specific fragmentation and molecular networking.

Journal: bioRxiv : the preprint server for biology

Published: June 12, 2025

Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells.

Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 12, 2025

Recognition of MR1-antigen complexes by TCR Vγ9Vδ2.

Recognition of MR1-antigen complexes by TCR Vγ9Vδ2.

Journal: Frontiers in immunology

Published: October 29, 2024

Nucleobase adducts bind MR1 and stimulate MR1-restricted T cells.

Nucleobase adducts bind MR1 and stimulate MR1-restricted T cells.

Journal: Science immunology

Published: May 10, 2024

MR1 Gene and Protein Expression Are Enhanced by Inhibition of the Extracellular Signal-Regulated Kinase ERK.

MR1 Gene and Protein Expression Are Enhanced by Inhibition of the Extracellular Signal-Regulated Kinase ERK.

Journal: Cancer immunology research

Published: February 01, 2024

The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells.

The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells.

Journal: Immunity

Published: October 06, 2023

Surface protein and functional analyses identify CD4+CD39+ TCR αβ+ and activated TCR Vδ1+ cells with distinct pro-inflammatory functions in Crohn's disease lesions.

Surface protein and functional analyses identify CD4+CD39+ TCR αβ+ and activated TCR Vδ1+ cells with distinct pro-inflammatory functions in Crohn's disease lesions.

Journal: Clinical and experimental immunology

Published: December 23, 2022

Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.

Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.

Journal: The Journal of experimental medicine

Published: November 11, 2022

Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties.

Phosphoproteomic mapping of CCR5 and ACKR2 signaling properties.

Journal: Frontiers in molecular biosciences

Published: October 03, 2022

MR1, an immunological periscope of cellular metabolism.

MR1, an immunological periscope of cellular metabolism.

Journal: International immunology

Published: July 14, 2021

Endogenous modification of the chemoattractant CXCL5 alters receptor usage and enhances its activity toward neutrophils and monocytes.

Endogenous modification of the chemoattractant CXCL5 alters receptor usage and enhances its activity toward neutrophils and monocytes.

Journal: Science signaling

Published: March 10, 2021

Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.

Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.

Journal: JCI insight

Published: November 06, 2020

Showing 1-12 of 23

Last Updated: 09/26/2026