Alessio V. Colombo

Munich, BY, Germany

Last Updated: 09/26/2026

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Found 24 publications

Distinct reduction in relative microglial glucose uptake compared to astrocytes and neurons upon isolation from the brain environment.

Distinct reduction in relative microglial glucose uptake compared to astrocytes and neurons upon isolation from the brain environment.

Journal: Frontiers in cellular neuroscience
Published: February 19, 2025

Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.

Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.

Journal: Science translational medicine
Published: December 04, 2024

Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.

Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.

Journal: Nature neuroscience
Published: August 14, 2024

Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover.

Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover.

Journal: Communications biology
Published: March 13, 2024

Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer's disease.

Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer's disease.

Journal: Cell death & disease
Published: March 19, 2021

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition.

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition.

Journal: eLife
Published: June 11, 2020

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.

Journal: eLife
Published: December 01, 2019

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.

Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.

Journal: Nature communications
Published: August 13, 2019

A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma.

A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma.

Journal: Journal of virology
Published: August 10, 2018

In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.

In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.

Journal: Glia
Published: April 06, 2018

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.

Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: April 05, 2018

BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.

BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.

Journal: PloS one
Published: February 13, 2018
Showing 1-12 of 24

Last Updated: 09/26/2026