Alexander Brohm
Stuttgart, BW, Germany
Last Updated: 09/26/2026
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Found 13 publications
Nucleosome linker DNA methylation by DNMT3A/DNMT3B3 is controlled by nucleosome binding and multimerization of DNMT3 complexes on DNA.
Journal: The Journal of biological chemistry
Published: June 17, 2025
SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain.
Journal: Nucleic acids research
Published: May 10, 2024
The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation.
Journal: The Journal of biological chemistry
Published: March 26, 2023
The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site.
Journal: Protein science : a publication of the Protein Society
Published: October 22, 2022
Methylation of recombinant mononucleosomes by DNMT3A demonstrates efficient linker DNA methylation and a role of H3K36me3.
Journal: Communications biology
Published: March 04, 2021
A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation.
Journal: Nucleic acids research
Published: February 12, 2021
Author Correction: Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate.
Journal: Communications biology
Published: October 20, 2020
Mechanistic Insights into the Allosteric Regulation of the Clr4 Protein Lysine Methyltransferase by Autoinhibition and Automethylation.
Journal: International journal of molecular sciences
Published: October 08, 2020
Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate.
Journal: Communications biology
Published: December 20, 2019
Somatic Cancer Mutations in the SUV420H1 Protein Lysine Methyltransferase Modulate Its Catalytic Activity.
Journal: Journal of molecular biology
Published: March 26, 2019
The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection.
Journal: Journal of molecular biology
Published: January 05, 2018
Last Updated: 09/26/2026