Alexandr V. Ilyaskin

Erlangen, BY, Germany

Last Updated: 09/26/2026

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Found 19 publications

Distinct functional roles of the GRIP domains in α-, β-, γ- and δ-ENaC.

Distinct functional roles of the GRIP domains in α-, β-, γ- and δ-ENaC.

Journal: The Journal of biological chemistry

Published: November 30, 2025

Differential modulation of polycystin-2 gain-of-function channels by cysteine-reactive compounds, amphiphilic substances, and S4-S5 linker mutations.

Differential modulation of polycystin-2 gain-of-function channels by cysteine-reactive compounds, amphiphilic substances, and S4-S5 linker mutations.

Journal: The Journal of biological chemistry

Published: March 31, 2025

Acute activation of human epithelial sodium channel (ENaC) by serum and glucocorticoid inducible kinase 1 (SGK1) requires prior cleavage of the channel's γ-subunit at its proximal cleavage site.

Acute activation of human epithelial sodium channel (ENaC) by serum and glucocorticoid inducible kinase 1 (SGK1) requires prior cleavage of the channel's γ-subunit at its proximal cleavage site.

Journal: Pflugers Archiv : European journal of physiology

Published: March 14, 2025

Automated patch-clamp recordings for detecting activators and inhibitors of the epithelial sodium channel (ENaC).

Automated patch-clamp recordings for detecting activators and inhibitors of the epithelial sodium channel (ENaC).

Journal: Pflugers Archiv : European journal of physiology

Published: January 24, 2025

Ion channel function of polycystin-2/polycystin-1 heteromer revealed by structure-guided mutagenesis.

Ion channel function of polycystin-2/polycystin-1 heteromer revealed by structure-guided mutagenesis.

Journal: FEBS letters

Published: January 09, 2025

Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney.

Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney.

Journal: Journal of the American Society of Nephrology : JASN

Published: March 25, 2024

Disease-associated missense mutations in the pore loop of polycystin-2 alter its ion channel function in a heterologous expression system.

Disease-associated missense mutations in the pore loop of polycystin-2 alter its ion channel function in a heterologous expression system.

Journal: The Journal of biological chemistry

Published: February 16, 2024

The small molecule activator S3969 stimulates the epithelial sodium channel by interacting with a specific binding pocket in the channel's β-subunit.

The small molecule activator S3969 stimulates the epithelial sodium channel by interacting with a specific binding pocket in the channel's β-subunit.

Journal: The Journal of biological chemistry

Published: September 25, 2023

Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit.

Transmembrane serine protease 2 (TMPRSS2) proteolytically activates the epithelial sodium channel (ENaC) by cleaving the channel's γ-subunit.

Journal: The Journal of biological chemistry

Published: December 23, 2021

Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels.

Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels.

Journal: American journal of physiology. Gastrointestinal and liver physiology

Published: November 10, 2021

Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice.

Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice.

Journal: Pflugers Archiv : European journal of physiology

Published: August 26, 2021

A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.

A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.

Journal: Journal of cell science

Published: June 09, 2021

Showing 1-12 of 19

Last Updated: 09/26/2026