Alexandra J. Noble

Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 13 publications

Specific Epigenetic Alterations Precede the Diagnosis of Inflammatory Bowel Disease in Adults in Northern Europe: Nationwide Analysis in Generation Scotland.

Specific Epigenetic Alterations Precede the Diagnosis of Inflammatory Bowel Disease in Adults in Northern Europe: Nationwide Analysis in Generation Scotland.

Journal: Gastroenterology

Published: February 14, 2026

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages.

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: August 28, 2025

Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis.

Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis.

Journal: Clinical epigenetics

Published: November 07, 2024

Development and validation of peripheral blood DNA methylation signatures to predict response to biological therapy in adults with Crohn's disease (EPIC-CD): an epigenome-wide association study.

Development and validation of peripheral blood DNA methylation signatures to predict response to biological therapy in adults with Crohn's disease (EPIC-CD): an epigenome-wide association study.

Journal: The lancet. Gastroenterology & hepatology

Published: August 28, 2024

Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region.

Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region.

Journal: EBioMedicine

Published: July 17, 2024

The Circulating Methylome in Childhood-Onset Inflammatory Bowel Disease.

The Circulating Methylome in Childhood-Onset Inflammatory Bowel Disease.

Journal: Journal of Crohn's & colitis

Published: April 08, 2024

Prenatal cannabis exposure is associated with alterations in offspring DNA methylation at genes involved in neurodevelopment, across the life course.

Prenatal cannabis exposure is associated with alterations in offspring DNA methylation at genes involved in neurodevelopment, across the life course.

Journal: Molecular psychiatry

Published: December 03, 2023

The impact of inversions across 33,924 families with rare disease from a national genome sequencing project.

The impact of inversions across 33,924 families with rare disease from a national genome sequencing project.

Journal: American journal of human genetics

Published: November 12, 2023

Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease.

Identification and validation of a blood- based diagnostic lipidomic signature of pediatric inflammatory bowel disease.

Journal: Nature communications

Published: May 19, 2023

Altered DNA methylation within DNMT3A, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease.

Altered DNA methylation within DNMT3A, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease.

Journal: Nature communications

Published: May 15, 2023

Defining Interactions Between the Genome, Epigenome, and the Environment in Inflammatory Bowel Disease: Progress and Prospects.

Defining Interactions Between the Genome, Epigenome, and the Environment in Inflammatory Bowel Disease: Progress and Prospects.

Journal: Gastroenterology

Published: August 15, 2022

Genome-Wide Methylation Profiling in 229 Patients With Crohn's Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn's Disease (TOPPIC).

Genome-Wide Methylation Profiling in 229 Patients With Crohn's Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn's Disease (TOPPIC).

Journal: Cellular and molecular gastroenterology and hepatology

Published: August 04, 2022

Showing 1-12 of 13

Last Updated: 09/26/2026