Alexandra Zielinski

Hamburg, HH, Germany

Last Updated: 09/26/2026

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Found 11 publications

6-[(1,4-Naphthoquinone-2-yl)methyl]thio-Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer.

6-[(1,4-Naphthoquinone-2-yl)methyl]thio-Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer.

Journal: Molecular cancer therapeutics

Published: October 23, 2024

Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins.

Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins.

Journal: Scientific reports

Published: January 28, 2024

Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer.

Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer.

Journal: International journal of molecular sciences

Published: October 16, 2022

Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance.

Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance.

Journal: International journal of molecular sciences

Published: October 05, 2022

DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients.

DNA Damage Response during Replication Correlates with CIN70 Score and Determines Survival in HNSCC Patients.

Journal: Cancers

Published: February 02, 2021

Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair.

Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair.

Journal: Cancers

Published: August 10, 2020

Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner.

Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization against PARP1 Inhibition in a Replication-Dependent Manner.

Journal: Cancers

Published: July 16, 2020

The POLD1R689W variant increases the sensitivity of colorectal cancer cells to ATR and CHK1 inhibitors.

The POLD1R689W variant increases the sensitivity of colorectal cancer cells to ATR and CHK1 inhibitors.

Journal: Scientific reports

Published: January 24, 2020

S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.

S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.

Journal: Cell cycle (Georgetown, Tex.)

Published: September 04, 2016

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress.

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress.

Journal: Oncotarget

Published: March 04, 2016

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response.

PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response.

Journal: Oncotarget

Published: July 07, 2015

Showing 1-11 of 11

Last Updated: 09/26/2026