Alexandre Leuci

Faculté De Médecine Lyon Est
Lyon, 69008, France

Last Updated: 09/26/2026

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Found 23 publications

Targeting synovitis by immunomodulation as a novel therapeutic approach for hemophilic arthropathy.

Targeting synovitis by immunomodulation as a novel therapeutic approach for hemophilic arthropathy.

Journal: Journal of thrombosis and haemostasis : JTH

Published: January 19, 2026

Inhibition of activated protein C anticoagulant function enhances coagulation but does not interrupt downstream mechanisms driving hemophilic arthropathy.

Inhibition of activated protein C anticoagulant function enhances coagulation but does not interrupt downstream mechanisms driving hemophilic arthropathy.

Journal: Experimental hematology

Published: December 18, 2025

In Vitro Study of the Role of Factor IX in Treatment of Breakthrough Bleeds in Patients with Hemophilia A and Inhibitors Receiving Emicizumab.

In Vitro Study of the Role of Factor IX in Treatment of Breakthrough Bleeds in Patients with Hemophilia A and Inhibitors Receiving Emicizumab.

Journal: TH open : companion journal to thrombosis and haemostasis

Published: November 13, 2025

Long-term durability of rAAV gene therapy in hemophilia: Factor expression, clinical outcomes and underlying molecular mechanisms.

Long-term durability of rAAV gene therapy in hemophilia: Factor expression, clinical outcomes and underlying molecular mechanisms.

Journal: Blood reviews

Published: August 17, 2025

Utilising Thrombin Generation Assay to Guide Co-Administration of Factor Therapies With Fitusiran.

Utilising Thrombin Generation Assay to Guide Co-Administration of Factor Therapies With Fitusiran.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia

Published: June 02, 2025

Discrepancy between one-stage clotting and chromogenic factor VIII activity in women with hemophilia A and hemophilia A carriers: a retrospective clinical study.

Discrepancy between one-stage clotting and chromogenic factor VIII activity in women with hemophilia A and hemophilia A carriers: a retrospective clinical study.

Journal: Journal of thrombosis and haemostasis : JTH

Published: October 16, 2024

Management of Abdominal Aortic Aneurysm Surgery in Glanzmann's Thrombasthenia Patients with Anti-GPIIb-IIIa Antibodies: A Case Report.

Management of Abdominal Aortic Aneurysm Surgery in Glanzmann's Thrombasthenia Patients with Anti-GPIIb-IIIa Antibodies: A Case Report.

Journal: Journal of clinical medicine

Published: July 22, 2024

Impaired microvascular function in patients with sickle cell anemia and leg ulcers improved with healing.

Impaired microvascular function in patients with sickle cell anemia and leg ulcers improved with healing.

Journal: British journal of haematology

Published: July 13, 2024

In vitro combined haemostatic efficacy of emicizumab and extended half-life factor VIII compounds.

In vitro combined haemostatic efficacy of emicizumab and extended half-life factor VIII compounds.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia

Published: July 05, 2024

Deciphering the circulating microRNA signature of hemophilic arthropathy.

Deciphering the circulating microRNA signature of hemophilic arthropathy.

Journal: Thrombosis research

Published: April 07, 2024

Whole F8 gene sequencing identified pathogenic structural variants in the remaining unsolved patients with severe hemophilia A.

Whole F8 gene sequencing identified pathogenic structural variants in the remaining unsolved patients with severe hemophilia A.

Journal: Journal of thrombosis and haemostasis : JTH

Published: December 18, 2023

Efanesoctocog alfa: the renaissance of Factor VIII replacement therapy.

Efanesoctocog alfa: the renaissance of Factor VIII replacement therapy.

Journal: Haematologica

Published: December 04, 2023

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Last Updated: 09/26/2026