Alexey V. Koval

Geneve, GE, Switzerland

Last Updated: 09/26/2026

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Found 61 publications

Safety and feasibility of oral zinc for patients with GNAO1-related disorders (ZINCGNAO1): an open-label, single-arm, single-centre, pilot trial in Germany.

Safety and feasibility of oral zinc for patients with GNAO1-related disorders (ZINCGNAO1): an open-label, single-arm, single-centre, pilot trial in Germany.

Journal: EClinicalMedicine
Published: May 26, 2026

Small-molecule inhibitor of Gαo for GNAO1 encephalopathy.

Small-molecule inhibitor of Gαo for GNAO1 encephalopathy.

Journal: Bioscience reports
Published: December 23, 2025

Loss of the conserved switch III region in a G protein leads to severe pediatric encephalopathy.

Loss of the conserved switch III region in a G protein leads to severe pediatric encephalopathy.

Journal: Science signaling
Published: October 28, 2025

Atypical GNAO1 variants in severe childhood speech disorders: clinical, genetic, and molecular insights.

Atypical GNAO1 variants in severe childhood speech disorders: clinical, genetic, and molecular insights.

Journal: Molecular autism
Published: October 07, 2025

Success and Controversy of Natural Products as Therapeutic Modulators of Wnt Signaling and Its Interplay with Oxidative Stress: Comprehensive Review Across Compound Classes and Experimental Systems.

Success and Controversy of Natural Products as Therapeutic Modulators of Wnt Signaling and Its Interplay with Oxidative Stress: Comprehensive Review Across Compound Classes and Experimental Systems.

Journal: Antioxidants (Basel, Switzerland)
Published: April 29, 2025

Syndecan-2 positively regulates Wnt/β-catenin signaling in breast cancer cells.

Syndecan-2 positively regulates Wnt/β-catenin signaling in breast cancer cells.

Journal: The international journal of biochemistry & cell biology
Published: April 06, 2025

Signalomics for molecular tumor boards and precision oncology of breast and gynecological cancers.

Signalomics for molecular tumor boards and precision oncology of breast and gynecological cancers.

Journal: Molecular systems biology
Published: March 16, 2025

A Personalized 14-3-3 Disease-Targeting Workflow Yields Repositioning Drug Candidates.

A Personalized 14-3-3 Disease-Targeting Workflow Yields Repositioning Drug Candidates.

Journal: Cells
Published: March 03, 2025

Challenging Reported Frizzled-Targeting Compounds in Selective Assays Reveals Lack of Functional Inhibition and Claimed Profiles.

Challenging Reported Frizzled-Targeting Compounds in Selective Assays Reveals Lack of Functional Inhibition and Claimed Profiles.

Journal: ACS pharmacology & translational science
Published: September 25, 2024

Germline mutations in a G protein identify signaling cross-talk in T cells.

Germline mutations in a G protein identify signaling cross-talk in T cells.

Journal: Science (New York, N.Y.)
Published: September 19, 2024

Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction.

Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction.

Journal: Genes & diseases
Published: August 13, 2024

Chemical and Biological Characterization of Metabolites from Silene viridiflora Using Mass Spectrometric and Cell-Based Assays.

Chemical and Biological Characterization of Metabolites from Silene viridiflora Using Mass Spectrometric and Cell-Based Assays.

Journal: Biomolecules
Published: August 07, 2024
Showing 1-12 of 61

Last Updated: 09/26/2026