Alexi J. Crosby

Cambridge, ENG CB20XY, United Kingdom

Last Updated: 09/26/2026

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Found 20 publications

Interleukin-6 is critical in the development of pulmonary vascular disease in Gcn2-deficient mice.

Interleukin-6 is critical in the development of pulmonary vascular disease in Gcn2-deficient mice.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 06, 2026

Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension.

Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension.

Journal: Pulmonary circulation
Published: April 28, 2020

4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension.

4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension.

Journal: American journal of respiratory cell and molecular biology
Published: April 08, 2020

miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.

miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension.

Journal: PloS one
Published: October 31, 2019

Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension.

Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension.

Journal: The European respiratory journal
Published: October 22, 2019

Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice.

Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 02, 2019

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice.

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice.

Journal: Pulmonary circulation
Published: August 31, 2018

A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension.

A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension.

Journal: British journal of pharmacology
Published: June 22, 2018

Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension.

Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension.

Journal: Thorax
Published: December 19, 2017

miR-322-5p targets IGF-1 and is suppressed in the heart of rats with pulmonary hypertension.

miR-322-5p targets IGF-1 and is suppressed in the heart of rats with pulmonary hypertension.

Journal: FEBS open bio
Published: August 29, 2017

CommWalker: correctly evaluating modules in molecular networks in light of annotation bias.

CommWalker: correctly evaluating modules in molecular networks in light of annotation bias.

Journal: Bioinformatics (Oxford, England)
Published: September 14, 2016

HIF2α-arginase axis is essential for the development of pulmonary hypertension.

HIF2α-arginase axis is essential for the development of pulmonary hypertension.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: July 20, 2016
Showing 1-12 of 20

Last Updated: 09/26/2026