Alf Spitschak

Alf Spitschak

Rostock, MV 18057, Germany

Last Updated: 09/26/2026

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Found 24 publications

Cancer in transition: discovery of tumor-intrinsic transcriptional programs shaping the immune and microenvironmental landscape.

Cancer in transition: discovery of tumor-intrinsic transcriptional programs shaping the immune and microenvironmental landscape.

Journal: Biomarker research
Published: February 03, 2026

Integrative Multimodal Profiling of TAp73 and DNp73 Reveals Isoform-Specific Transcriptomic Coregulator Landscapes in Cancer Programs.

Integrative Multimodal Profiling of TAp73 and DNp73 Reveals Isoform-Specific Transcriptomic Coregulator Landscapes in Cancer Programs.

Journal: Biomolecules
Published: November 27, 2025

CD8+ T Cell Subsets as Biomarkers for Predicting Checkpoint Therapy Outcomes in Cancer Immunotherapy.

CD8+ T Cell Subsets as Biomarkers for Predicting Checkpoint Therapy Outcomes in Cancer Immunotherapy.

Journal: Biomedicines
Published: February 27, 2025

TAp73α drives cancer metastasis via PPI-mediated derepression of the neuronal HDAC2/REST-GABBR2 axis.

TAp73α drives cancer metastasis via PPI-mediated derepression of the neuronal HDAC2/REST-GABBR2 axis.

Journal: Cancer letters
Published: January 15, 2025

E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsiveness.

E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsiveness.

Journal: Frontiers in immunology
Published: July 25, 2024

Drug Repurposing at the Interface of Melanoma Immunotherapy and Autoimmune Disease.

Drug Repurposing at the Interface of Melanoma Immunotherapy and Autoimmune Disease.

Journal: Pharmaceutics
Published: September 23, 2022

Novel integrated workflow allows production and in-depth quality assessment of multifactorial reprogrammed skeletal muscle cells from human stem cells.

Novel integrated workflow allows production and in-depth quality assessment of multifactorial reprogrammed skeletal muscle cells from human stem cells.

Journal: Cellular and molecular life sciences : CMLS
Published: December 15, 2021

Mechanisms of Functional Pleiotropy of p73 in Cancer and Beyond.

Mechanisms of Functional Pleiotropy of p73 in Cancer and Beyond.

Journal: Frontiers in cell and developmental biology
Published: July 07, 2021

LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1.

LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1.

Journal: Theranostics
Published: January 21, 2020

Adenoviral mediated expression of anti-inflammatory progranulin by placental explants modulates endothelial cell activation by decrease of ICAM-1 expression.

Adenoviral mediated expression of anti-inflammatory progranulin by placental explants modulates endothelial cell activation by decrease of ICAM-1 expression.

Journal: Placenta
Published: July 28, 2019

Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness.

Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness.

Journal: Journal of experimental & clinical cancer research : CR
Published: April 15, 2019

Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers.

Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers.

Journal: Theranostics
Published: August 28, 2018
Showing 1-12 of 24

Last Updated: 09/26/2026