Alfie R. Wearn

Newcastle Upon Tyne, ENG NE17RU, United Kingdom

Last Updated: 09/26/2026

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Found 25 publications

Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.

Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.

Journal: bioRxiv : the preprint server for biology

Published: January 23, 2026

Cortical microstructural integrity predicts an exploitation bias in older adulthood.

Cortical microstructural integrity predicts an exploitation bias in older adulthood.

Journal: The journals of gerontology. Series B, Psychological sciences and social sciences

Published: December 08, 2025

Reading for wellbeing: a realist review of evidence.

Reading for wellbeing: a realist review of evidence.

Journal: Perspectives in public health

Published: December 01, 2025

The neuromodulatory fragility hypothesis of Alzheimer's disease pathogenesis.

The neuromodulatory fragility hypothesis of Alzheimer's disease pathogenesis.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: November 30, 2025

Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.

Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: November 30, 2025

Cholinergic synaptic plasticity shapes resilience and vulnerability to tau.

Cholinergic synaptic plasticity shapes resilience and vulnerability to tau.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer's disease pathology.

Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer's disease pathology.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: October 27, 2025

The PREVENT-AD cohort: accelerating Alzheimer's disease research and treatment in Canada and beyond.

The PREVENT-AD cohort: accelerating Alzheimer's disease research and treatment in Canada and beyond.

Journal: medRxiv : the preprint server for health sciences

Published: August 08, 2025

The PREVENT-AD cohort: Accelerating Alzheimer's disease research and treatment in Canada and beyond.

The PREVENT-AD cohort: Accelerating Alzheimer's disease research and treatment in Canada and beyond.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: March 25, 2025

Hemoglobin in the brain frontal lobe tissue of patients with Alzheimer's disease is susceptible to reactive nitrogen species-mediated oxidative damage.

Hemoglobin in the brain frontal lobe tissue of patients with Alzheimer's disease is susceptible to reactive nitrogen species-mediated oxidative damage.

Journal: Redox biology

Published: February 19, 2025

Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease.

Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease.

Journal: Neurobiology of aging

Published: September 25, 2024

Corrigendum: L-DOPA increases slow-wave sleep duration and selectively modulates memory persistence in older adults.

Corrigendum: L-DOPA increases slow-wave sleep duration and selectively modulates memory persistence in older adults.

Journal: Frontiers in behavioral neuroscience

Published: August 09, 2024

Showing 1-12 of 25

Last Updated: 09/26/2026