Alfonso Orovio-Bueno

Parks Rd
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 73 publications

T-World Virtual Human Cardiomyocyte. II. Organ-Scale Simulations and Applications.

T-World Virtual Human Cardiomyocyte. II. Organ-Scale Simulations and Applications.

Journal: Circulation research

Published: April 08, 2026

T-World Virtual Human Cardiomyocyte. I. Development, Validation, and Cell Arrhythmogenesis.

T-World Virtual Human Cardiomyocyte. I. Development, Validation, and Cell Arrhythmogenesis.

Journal: Circulation research

Published: April 07, 2026

Hypertrophic cardiomyopathy caused by filamin-C variants has restrictive and extracardiac features and a distinctive ECG.

Hypertrophic cardiomyopathy caused by filamin-C variants has restrictive and extracardiac features and a distinctive ECG.

Journal: Heart rhythm

Published: September 15, 2025

Simulation-based digital twinning of activation and repolarisation sequences from the ECG across healthy and diseased hearts.

Simulation-based digital twinning of activation and repolarisation sequences from the ECG across healthy and diseased hearts.

Journal: Computers in biology and medicine

Published: June 30, 2025

Toward cardiac electrophysiology digital twins with an efficient open source scalable solver on GPU clusters.

Toward cardiac electrophysiology digital twins with an efficient open source scalable solver on GPU clusters.

Journal: Scientific reports

Published: April 08, 2025

T-World: A highly general computational model of a human ventricular myocyte.

T-World: A highly general computational model of a human ventricular myocyte.

Journal: bioRxiv : the preprint server for biology

Published: April 08, 2025

Artificial intelligence applications in hypertrophic cardiomyopathy: turns and loopholes.

Artificial intelligence applications in hypertrophic cardiomyopathy: turns and loopholes.

Journal: European heart journal. Digital health

Published: February 25, 2025

Rational design, synthesis, and evaluation of novel polypharmacological compounds targeting NaV1.5, KV1.5, and K2P channels for atrial fibrillation.

Rational design, synthesis, and evaluation of novel polypharmacological compounds targeting NaV1.5, KV1.5, and K2P channels for atrial fibrillation.

Journal: The Journal of biological chemistry

Published: July 20, 2024

Prospective in silico trials identify combined SK and K2P channel block as an effective strategy for atrial fibrillation cardioversion.

Prospective in silico trials identify combined SK and K2P channel block as an effective strategy for atrial fibrillation cardioversion.

Journal: The Journal of physiology

Published: June 18, 2024

In Silico TRials guide optimal stratification of ATrIal FIbrillation patients to Catheter Ablation and pharmacological medicaTION: the i-STRATIFICATION study.

In Silico TRials guide optimal stratification of ATrIal FIbrillation patients to Catheter Ablation and pharmacological medicaTION: the i-STRATIFICATION study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Published: March 20, 2024

Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy.

Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy.

Journal: Frontiers in pharmacology

Published: January 30, 2024

Harnessing 12-lead ECG and MRI data to personalise repolarisation profiles in cardiac digital twin models for enhanced virtual drug testing.

Harnessing 12-lead ECG and MRI data to personalise repolarisation profiles in cardiac digital twin models for enhanced virtual drug testing.

Journal: Medical image analysis

Published: January 18, 2024

Showing 1-12 of 73

Last Updated: 09/26/2026