Alfred O. Vertegaal

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 87 publications

Survey of the human proteostasis network: the ubiquitin-proteasome system.

Survey of the human proteostasis network: the ubiquitin-proteasome system.

Journal: bioRxiv : the preprint server for biology

Published: March 27, 2026

A Landscape Analysis of Human SUMOylation.

A Landscape Analysis of Human SUMOylation.

Journal: Molecular & cellular proteomics : MCP

Published: November 03, 2025

Interaction networks of SIM-binding groove mutants reveal alternate modes of SUMO binding and profound impact on SUMO conjugation.

Interaction networks of SIM-binding groove mutants reveal alternate modes of SUMO binding and profound impact on SUMO conjugation.

Journal: Science advances

Published: May 14, 2025

Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia.

Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia.

Journal: The Journal of cell biology

Published: May 09, 2025

Pharmacological CLK inhibition disrupts SR protein function and RNA splicing blocking cell growth and migration in TNBC.

Pharmacological CLK inhibition disrupts SR protein function and RNA splicing blocking cell growth and migration in TNBC.

Journal: Breast cancer research : BCR

Published: March 26, 2025

Lrif1 modulates Trim28-mediated repression of the Dux locus in mouse embryonic stem cells.

Lrif1 modulates Trim28-mediated repression of the Dux locus in mouse embryonic stem cells.

Journal: bioRxiv : the preprint server for biology

Published: November 28, 2024

SUMO2/3 modification of transcription-associated proteins controls cell viability in response to oxygen and glucose deprivation-mediated stress.

SUMO2/3 modification of transcription-associated proteins controls cell viability in response to oxygen and glucose deprivation-mediated stress.

Journal: Cell death discovery

Published: October 29, 2024

Cell cycle arrest enhances CD8+ T cell effector function by potentiating glucose metabolism and IL-2 signaling.

Cell cycle arrest enhances CD8+ T cell effector function by potentiating glucose metabolism and IL-2 signaling.

Journal: Nature immunology

Published: August 22, 2024

Targeting epigenetic regulation and post-translational modification with 5-Aza-2' deoxycytidine and SUMO E1 inhibition augments T-cell receptor therapy.

Targeting epigenetic regulation and post-translational modification with 5-Aza-2' deoxycytidine and SUMO E1 inhibition augments T-cell receptor therapy.

Journal: Journal for immunotherapy of cancer

Published: June 07, 2024

CFAP20 salvages arrested RNAPII from the path of co-directional replisomes.

CFAP20 salvages arrested RNAPII from the path of co-directional replisomes.

Journal: Nature

Published: May 19, 2024

Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability.

Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability.

Journal: PLoS genetics

Published: January 19, 2024

SUMO proteases: from cellular functions to disease.

SUMO proteases: from cellular functions to disease.

Journal: Trends in cell biology

Published: November 17, 2023

Showing 1-12 of 87

Last Updated: 09/26/2026