Ali S. Abdelhameed

Riyadh, 11451, Saudi Arabia

Last Updated: 09/26/2026

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Found 131 publications

Development of metal-free one-pot sequential synthesis of carbazolyl-thiazolidinones as anti-leukemic agents with potential β-catenin/c-MYC pathway modulation: from synthesis to in vitro and in silico profiling.

Development of metal-free one-pot sequential synthesis of carbazolyl-thiazolidinones as anti-leukemic agents with potential β-catenin/c-MYC pathway modulation: from synthesis to in vitro and in silico profiling.

Journal: Bioorganic chemistry

Published: May 30, 2026

Quantification of buparlisib in human liver microsomes employing an ultra-fast, sensitive UPLC-MS/MS method: in vitro and in silico metabolic stability evaluation.

Quantification of buparlisib in human liver microsomes employing an ultra-fast, sensitive UPLC-MS/MS method: in vitro and in silico metabolic stability evaluation.

Journal: The Analyst

Published: January 27, 2026

Estimation of the metabolic stability of omipalisib in human liver microsomes employing an ultra-fast UPLC-MS/MS approach: in silico screening for structural alarms and metabolic lability.

Estimation of the metabolic stability of omipalisib in human liver microsomes employing an ultra-fast UPLC-MS/MS approach: in silico screening for structural alarms and metabolic lability.

Journal: Analytical methods : advancing methods and applications

Published: January 26, 2026

C-Ring Structure-Dependent Redox Properties of Flavonoids Regulate the Expression of Bioactivity.

C-Ring Structure-Dependent Redox Properties of Flavonoids Regulate the Expression of Bioactivity.

Journal: Antioxidants (Basel, Switzerland)

Published: December 03, 2025

Determination of veliparib metabolic stability in the human liver microsomes using a hydrophilic interaction UPLC-MS/MS quantitative method: greenness assessment with an in silico study for ADME, DEREK alarms and metabolic lability.

Determination of veliparib metabolic stability in the human liver microsomes using a hydrophilic interaction UPLC-MS/MS quantitative method: greenness assessment with an in silico study for ADME, DEREK alarms and metabolic lability.

Journal: The Analyst

Published: November 13, 2025

Development and validation of a quick and sensitive UPLC-MS/MS method for measuring ensartinib in HLMs: investigation of structural alerts associated with metabolic lability and in silico toxicity.

Development and validation of a quick and sensitive UPLC-MS/MS method for measuring ensartinib in HLMs: investigation of structural alerts associated with metabolic lability and in silico toxicity.

Journal: The Analyst

Published: November 06, 2025

Green Ultra-Fast UPLC-MS/MS Method for Enasidenib Quantification in HLMs Matrix With the Metabolic Stability Assessment: In Silico Study for Structural Alerts, ADME Characteristics and Metaboslic Lability.

Green Ultra-Fast UPLC-MS/MS Method for Enasidenib Quantification in HLMs Matrix With the Metabolic Stability Assessment: In Silico Study for Structural Alerts, ADME Characteristics and Metaboslic Lability.

Journal: Biomedical chromatography : BMC

Published: September 27, 2025

Assessment of the metabolic stability of avapritinib in human liver microsomes using a fast and green UPLC-MS/MS method: screening for structural alarms associated with metabolic lability and in silico toxicity.

Assessment of the metabolic stability of avapritinib in human liver microsomes using a fast and green UPLC-MS/MS method: screening for structural alarms associated with metabolic lability and in silico toxicity.

Journal: Analytical methods : advancing methods and applications

Published: September 08, 2025

Evaluation of Anlotinib Metabolic Stability in HLMs Matrix Applying Ultra-Fast UPLC-MS/MS Approach: Greenness Assessment With In Silico Testing for Structural Alarms Related to the Metabolic Lability and DEREK Toxicity.

Evaluation of Anlotinib Metabolic Stability in HLMs Matrix Applying Ultra-Fast UPLC-MS/MS Approach: Greenness Assessment With In Silico Testing for Structural Alarms Related to the Metabolic Lability and DEREK Toxicity.

Journal: Biomedical chromatography : BMC

Published: August 19, 2025

Cellular cAMP Content and Mitochondrial Profile Define Different Subtypes of Ovarian Cancer Cells.

Cellular cAMP Content and Mitochondrial Profile Define Different Subtypes of Ovarian Cancer Cells.

Journal: International journal of molecular sciences

Published: August 12, 2025

Ultra-Fast Green UPLC-MS/MS Method for the Quantification of Cediranib in the Human Liver Microsome Matrix: In Vitro and In Silico Metabolic Stability Assessment.

Ultra-Fast Green UPLC-MS/MS Method for the Quantification of Cediranib in the Human Liver Microsome Matrix: In Vitro and In Silico Metabolic Stability Assessment.

Journal: Archiv der Pharmazie

Published: August 11, 2025

Mitigating testicular dysfunction: Metformin's role in combating valproic acid-induced damage in rats.

Mitigating testicular dysfunction: Metformin's role in combating valproic acid-induced damage in rats.

Journal: Reproductive biology

Published: July 23, 2025

Showing 1-12 of 131

Last Updated: 09/26/2026