Aline Fuchs

Lausanne, VD, Switzerland

Last Updated: 09/26/2026

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Found 26 publications

Elimination of tau tangles and soluble aggregates with the small molecule ACI-16664 prevents neurodegeneration in vivo.

Elimination of tau tangles and soluble aggregates with the small molecule ACI-16664 prevents neurodegeneration in vivo.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: December 09, 2025

Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD.

Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD.

Journal: Acta neuropathologica communications

Published: April 30, 2024

Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework.

Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework.

Journal: mAbs

Published: July 06, 2023

Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF.

Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF.

Journal: Brain communications

Published: June 12, 2023

Predicting Optimal Antimalarial Drug Combinations from a Standardized Plasmodium falciparum Humanized Mouse Model.

Predicting Optimal Antimalarial Drug Combinations from a Standardized Plasmodium falciparum Humanized Mouse Model.

Journal: Antimicrobial agents and chemotherapy

Published: May 03, 2023

Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study.

Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study.

Journal: The Lancet. Infectious diseases

Published: July 13, 2021

Dosing strategies of imipenem in neonates based on pharmacometric modelling and simulation.

Dosing strategies of imipenem in neonates based on pharmacometric modelling and simulation.

Journal: The Journal of antimicrobial chemotherapy

Published: May 18, 2021

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.

Journal: Nature communications

Published: May 17, 2021

Defining the Antimalarial Activity of Cipargamin in Healthy Volunteers Experimentally Infected with Blood-Stage Plasmodium falciparum.

Defining the Antimalarial Activity of Cipargamin in Healthy Volunteers Experimentally Infected with Blood-Stage Plasmodium falciparum.

Journal: Antimicrobial agents and chemotherapy

Published: July 13, 2020

The kinetic profiles of copeptin and mid regional proadrenomedullin (MR-proADM) in pediatric lower respiratory tract infections.

The kinetic profiles of copeptin and mid regional proadrenomedullin (MR-proADM) in pediatric lower respiratory tract infections.

Journal: PloS one

Published: March 26, 2020

Amoxicillin Dosing Regimens for the Treatment of Neonatal Sepsis: Balancing Efficacy and Neurotoxicity.

Amoxicillin Dosing Regimens for the Treatment of Neonatal Sepsis: Balancing Efficacy and Neurotoxicity.

Journal: Neonatology

Published: March 18, 2020

Optimisation of vancomycin exposure in neonates based on the best level of evidence.

Optimisation of vancomycin exposure in neonates based on the best level of evidence.

Journal: Pharmacological research

Published: February 05, 2019

Showing 1-12 of 26

Last Updated: 09/26/2026