Alistair K. Brown
Newcastle Upon Tyne, ENG NE24HH, United Kingdom
Last Updated: 09/26/2026
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Found 12 publications
3-(Pyridine-3-ylmethylene)chroman-4-one and tetralone derivatives: synthesis, Mycobacterium tuberculosis CYP121A1 enzyme inhibition and antimycobacterial activity vs drug-sensitive and drug-resistant strains.
Journal: RSC medicinal chemistry
Published: August 22, 2025
Structural isomerisation affects the antitubercular activity of adamantyl-isoxyl adducts.
Journal: Journal of enzyme inhibition and medicinal chemistry
Published: May 21, 2025
Cryo-electron microscopy structure of the di-domain core of Mycobacterium tuberculosis polyketide synthase 13, essential for mycobacterial mycolic acid synthesis.
Journal: Microbiology (Reading, England)
Published: October 16, 2024
A stereodivergent multicomponent approach for the synthesis of C-N atropisomeric peptide analogues.
Journal: Chemical science
Published: July 15, 2024
Feline pyothorax caused by tooth aspiration.
Journal: The Journal of small animal practice
Published: July 11, 2023
Identification of Substituted Amino Acid Hydrazides as Novel Anti-Tubercular Agents, Using a Scaffold Hopping Approach.
Journal: Molecules (Basel, Switzerland)
Published: April 22, 2020
Identification of Novel Benzoxa-[2,1,3]-diazole Substituted Amino Acid Hydrazides as Potential Anti-Tubercular Agents.
Journal: Molecules (Basel, Switzerland)
Published: January 29, 2019
Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation.
Journal: Acta crystallographica. Section D, Structural biology
Published: September 27, 2018
Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis.
Journal: European journal of medicinal chemistry
Published: November 24, 2016
Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethylocta-2,6-dienyl)ethane-1,2-diamine (SQ109) Pyrrole Hybrid Derivatives: Discovery of Potent Antitubercular Agents Effective against Multidrug-Resistant Mycobacteria.
Journal: Journal of medicinal chemistry
Published: February 25, 2016
VapC20 of Mycobacterium tuberculosis cleaves the sarcin-ricin loop of 23S rRNA.
Journal: Nature communications
Published: May 01, 2013
Showing 1-12 of 12
Last Updated: 09/26/2026