Alistair N. Hume

Nottingham, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 22 publications

Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution.

Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution.

Journal: Communications biology

Published: August 25, 2023

Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding.

Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding.

Journal: Journal of clinical immunology

Published: November 01, 2021

Determination of the Rab27-Effector Binding Affinity Using a High-Throughput FRET-Based Assay.

Determination of the Rab27-Effector Binding Affinity Using a High-Throughput FRET-Based Assay.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: August 28, 2021

GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.

GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.

Journal: Blood advances

Published: March 22, 2021

In Vitro Fluorescence Resonance Energy Transfer-Based Assay Used to Determine the Rab27-Effector-Binding Affinity.

In Vitro Fluorescence Resonance Energy Transfer-Based Assay Used to Determine the Rab27-Effector-Binding Affinity.

Journal: Assay and drug development technologies

Published: May 09, 2020

The adaptor protein melanophilin regulates dynamic myosin-Va:cargo interaction and dendrite development in melanocytes.

The adaptor protein melanophilin regulates dynamic myosin-Va:cargo interaction and dendrite development in melanocytes.

Journal: Molecular biology of the cell

Published: January 31, 2019

Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins.

Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins.

Journal: Nature communications

Published: April 14, 2018

Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a.

Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a.

Journal: Journal of cell science

Published: October 10, 2017

Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro.

Myosin Va's adaptor protein melanophilin enforces track selection on the microtubule and actin networks in vitro.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 01, 2017

Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.

Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.

Journal: eLife

Published: May 05, 2016

Correction: A Role for Na+,K+-ATPase α1 in Regulating Rab27a Localisation on Melanosomes.

Correction: A Role for Na+,K+-ATPase α1 in Regulating Rab27a Localisation on Melanosomes.

Journal: PloS one

Published: February 04, 2016

Inefficient recruitment of kinesin-1 to melanosomes precludes it from facilitating their transport.

Inefficient recruitment of kinesin-1 to melanosomes precludes it from facilitating their transport.

Journal: Journal of cell science

Published: January 15, 2016

Showing 1-12 of 22

Last Updated: 09/26/2026