Allison P. Dane

Guy's And St. Thomas' Hospital, Newcastle And Freeline Therapeutics
Stevenage, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 15 publications

FLT201, a novel liver-directed AAV gene therapy candidate for Gaucher disease type 1.

FLT201, a novel liver-directed AAV gene therapy candidate for Gaucher disease type 1.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: December 10, 2024

Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B.

Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B.

Journal: The New England journal of medicine

Published: July 20, 2022

Recombinant Adeno-Associated Viral Vectors Expressing Human Coagulation FIX-E456H Variant in Hemophilia B Mice.

Recombinant Adeno-Associated Viral Vectors Expressing Human Coagulation FIX-E456H Variant in Hemophilia B Mice.

Journal: Thrombosis and haemostasis

Published: October 30, 2019

Potential limits of AAV-based gene therapy with the use of new transgenes expressing factor IX fusion proteins.

Potential limits of AAV-based gene therapy with the use of new transgenes expressing factor IX fusion proteins.

Journal: Haemophilia : the official journal of the World Federation of Hemophilia

Published: February 19, 2018

Partial pancreatic transdifferentiation of primary human hepatocytes in the livers of a humanised mouse model.

Partial pancreatic transdifferentiation of primary human hepatocytes in the livers of a humanised mouse model.

Journal: The journal of gene medicine

Published: November 28, 2017

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: March 27, 2017

Identification of liver-specific enhancer-promoter activity in the 3' untranslated region of the wild-type AAV2 genome.

Identification of liver-specific enhancer-promoter activity in the 3' untranslated region of the wild-type AAV2 genome.

Journal: Nature genetics

Published: December 15, 2016

Transient suppression of hepatocellular replication in the mouse liver following transduction with recombinant adeno-associated virus.

Transient suppression of hepatocellular replication in the mouse liver following transduction with recombinant adeno-associated virus.

Journal: Gene therapy

Published: January 11, 2015

Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability.

Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability.

Journal: CPT: pharmacometrics & systems pharmacology

Published: January 27, 2014

Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice.

Transient inflammatory-like state and microbial dysbiosis are pivotal in establishment of mucosal homeostasis during colonisation of germ-free mice.

Journal: Beneficial microbes

Published: December 11, 2013

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.

Journal: Nature

Published: July 24, 2013

Adeno-associated virus-mediated rescue of neonatal lethality in argininosuccinate synthetase-deficient mice.

Adeno-associated virus-mediated rescue of neonatal lethality in argininosuccinate synthetase-deficient mice.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: April 04, 2013

Showing 1-12 of 15

Last Updated: 09/26/2026