Alvaro O. Ardiles

Valparaiso, VS, Chile

Last Updated: 09/26/2026

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Found 38 publications

Metformin enhances hippocampal excitatory synaptic transmission and preserves synaptic plasticity under amyloid-β oligomer-induced dysfunction.

Metformin enhances hippocampal excitatory synaptic transmission and preserves synaptic plasticity under amyloid-β oligomer-induced dysfunction.

Journal: Neuropharmacology

Published: February 06, 2026

Disrupted brain angiogenesis and blood-brain barrier function underlie cognitive deficits in offspring of preeclampsia-like pregnancies.

Disrupted brain angiogenesis and blood-brain barrier function underlie cognitive deficits in offspring of preeclampsia-like pregnancies.

Journal: The Journal of physiology

Published: September 26, 2025

Gestational hypothyroxinemia causes an inflammatory environment at maternal-fetal tissues and fetal brain with impaired hippocampal dendritic spine maturation in the offspring.

Gestational hypothyroxinemia causes an inflammatory environment at maternal-fetal tissues and fetal brain with impaired hippocampal dendritic spine maturation in the offspring.

Journal: Scientific reports

Published: July 08, 2025

Boldo leaves reduce seizures, neuroinflammation, and hemichannel activity in a murine model of chronic epilepsy.

Boldo leaves reduce seizures, neuroinflammation, and hemichannel activity in a murine model of chronic epilepsy.

Journal: Biological research

Published: July 07, 2025

The synaptic availability of GluA1 is reduced in hippocampal neurons of a murine model of dynamin-2 linked autosomal dominant centronuclear myopathy.

The synaptic availability of GluA1 is reduced in hippocampal neurons of a murine model of dynamin-2 linked autosomal dominant centronuclear myopathy.

Journal: Science progress

Published: April 02, 2025

Pannexin 1 channels: A bridge between synaptic plasticity and learning and memory processes.

Pannexin 1 channels: A bridge between synaptic plasticity and learning and memory processes.

Journal: Neuroscience and biobehavioral reviews

Published: February 11, 2025

Excitatory-inhibitory synaptic imbalance induced by acute intra-hippocampus injections of amyloid-β oligomers.

Excitatory-inhibitory synaptic imbalance induced by acute intra-hippocampus injections of amyloid-β oligomers.

Journal: Biochemical and biophysical research communications

Published: October 04, 2024

Ca2+ permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death.

Ca2+ permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 11, 2024

The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes.

The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes.

Journal: Journal of neurochemistry

Published: October 24, 2023

Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity.

Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity.

Journal: Biomolecules

Published: May 04, 2023

Probenecid, an Old Drug with Potential New Uses for Central Nervous System Disorders and Neuroinflammation.

Probenecid, an Old Drug with Potential New Uses for Central Nervous System Disorders and Neuroinflammation.

Journal: Biomedicines

Published: March 20, 2023

mGluR-dependent plasticity in rodent models of Alzheimer's disease.

mGluR-dependent plasticity in rodent models of Alzheimer's disease.

Journal: Frontiers in synaptic neuroscience

Published: December 13, 2022

Showing 1-12 of 38

Last Updated: 09/26/2026